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Introduction: Aggression and violence, people's inhumanity to one another, are perhaps society's foremost problems. One approach to this problem is the provision of traditional clinical services through psychotherapy. Anger control is a learnable skill, but such learning requires "time on task." Our goal was to shed light on the potential impact of psychotherapy as a public health remedy, by studying how much psychotherapeutic intervention is being delivered to patients with impulsive aggression classified as Intermittent Explosive Disorder (IED).
Method: Using de-identified electronic health record data from TriNetX, collected from 87 medical institutions, we analyzed the distribution of psychotherapeutic sessions received by 32,322 individuals with IED.
Results: The distribution of psychotherapeutic sessions is highly skewed, resembling a curve of inverse proportion. The mode and the median for sessions attended were zero; the mean was four sessions. Only about 25% of patients received any psychotherapy. Approximately 10% attended nine visits or more; 5% 30 or more; 2% 50 or more. Eighty percent of the psychotherapeutic labor went to the 7.5% of patients who could attend over 14 sessions; about half the psychotherapeutic labor went to the 2.5% of patients who could attend 40 or more sessions. Thus, a small subset of patients absorbed most of the psychotherapeutic labor, and most patients did not spend enough (or even any) psychotherapeutic time on task.
Discussion: Traditional psychotherapy delivered through health care systems appears to deliver sufficient "time on task" to only a small subset of individuals with impulsive aggression. Multipronged public health solutions to aggression and violence must be pursued by society as a whole. The efforts of mental health professionals are important and necessary, but the job should not be delegated to clinicians alone.
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http://dx.doi.org/10.3389/fpubh.2025.1570642 | DOI Listing |
Arch Psychiatr Nurs
October 2025
Xiangya School of Nursing, Central South University, Changsha, Hunan Province, China; School of Nursing, Changsha Medical University, 1501 Leifeng Avenue, Wangcheng district, Changsha, Hunan 410219, China. Electronic address:
Objectives: This study aimed to assess antipsychotic medication non-adherence among patients with schizophrenia in Ethiopia, and to explore its associated factors based on the Multidimensional Adherence Model.
Methods: This study is a cross-sectional study using convenience sampling enrolled 406 schizophrenia patients from July 17 to August 25, 2023. Data collection included medication non-adherence, sociodemographic factors, patient-related factors, therapy-related factors, condition-related factors, and healthcare system-related factors.
J Affect Disord
September 2025
CORE Data Lab, University College London, 1-19 Torrington Place, London, WC1E 7HB, UK; Research Department of Clinical, Educational and Health Psychology, University College London, 1-19 Torrington Place, London, WC1E 7HB, UK; iCope, Camden and Islington NHS Talking Therapies for anxiety and depress
Background: Anhedonia, the lack of interest or pleasure in activities, is a core but under-addressed symptom of depression. Consequently, little is known about the efficacy of treatments for alleviating anhedonia.
Objective: To evaluate the efficacy of psychotherapeutic and pharmacological treatments for depression at reducing symptoms of anhedonia.
Carbohydr Polym
November 2025
Department of Pharmacy - Pharmaceutical Sciences, University of Bari Aldo Moro, E. Orabona St., 70125 Bari, Italy.
Direct printing of pharmaceutical powders allows the creation of personalized paediatric dosage forms, such as orodispersible films (ODFs). In this study, we present an optimized protocol to prepare midazolam (MDZ)/γ-cyclodextrin (γ-CD) inclusion complex-loaded ODFs using the innovative direct powder extrusion 3D printing technique (DPE). ODFs were formulated with a polymer blend consisting of polyethylene oxide and hydroxypropyl methylcellulose, in the presence or without γ-CD.
View Article and Find Full Text PDFCureus
August 2025
Pulmonary and Critical Care Medicine, HCA Houston Healthcare Kingwood/University of Houston, Kingwood, USA.
Pulmonary toxicity is a serious yet frequently under-recognized complication of antidepressant therapy. With the continued rise in prescriptions, awareness of potential respiratory adverse effects is crucial. This review outlines documented cases of lung injury linked to various antidepressant classes, including selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), atypical antidepressants, serotonin modulators, tricyclic antidepressants (TCAs), and monoamine oxidase inhibitors (MAOIs).
View Article and Find Full Text PDFDrug Des Devel Ther
September 2025
Zhejiang University School of Medicine, Hangzhou, People's Republic of China.
Background: Depression is a complex neuropsychiatric disorder involving neuroinflammation, synaptic dysfunction, and neurotransmitter dysregulation. Recent studies have highlighted the therapeutic potential of short-acting anesthetics in the treatment of depression. Ciprofol, a novel intravenous anesthetic with rapid onset and recovery, shows promise, although its antidepressant mechanisms remain underexplored.
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