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Type 1 diabetes (T1DM) is one of the most common chronic metabolic diseases in the world. Insulin replacement therapy and drug adjuvant therapy are the main means of modern medical treatment of T1DM; still, there are adverse reactions such as drug resistance, which seriously hinder the therapeutic effect. As a unique medical method in China, traditional Chinese medicine (TCM) has a significant effect on the treatment of T1DM. TCM therapy can reduce the symptoms of T1DM, prevent complications, improve insulin resistance, and promote insulin secretion. In recent years, the research field of TCM in the treatment of T1DM has made considerable progress. The research on the treatment of T1DM by Chinese herbal medicine, TCM prescription, acupuncture, and moxibustion shows good anti-T1DM effect and significantly improves the survival rate of patients. This article aims to summarize the methods of TCM in the treatment of T1DM, expounds on the mechanism of action in the treatment of T1DM, and discusses the limitations and opportunities of TCM in the treatment of T1DM.
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http://dx.doi.org/10.1002/ptr.8514 | DOI Listing |
Pediatr Diabetes
September 2025
Pediatric Endocrinology Department, Gaafar Ibn Auf Pediatric Tertiary Hospital, Khartoum, Sudan.
Mauriac syndrome (MS) is a rare condition linked to inadequate glycemic control in type 1 diabetes mellitus (T1DM) and has also rarely been reported in patients with neonatal diabetes. MS manifests as growth failure, delayed puberty, cushingoid features, and hepatomegaly. The condition can be associated with complications like dyslipidemia, retinopathy, and nephropathy.
View Article and Find Full Text PDFJ Diabetes Res
September 2025
Department of Endocrinology, Shenzhen Third People's Hospital, The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong Province, China.
This study was to explore the causal effect of iron status on renal function and the risk of diabetic nephropathy in diabetic patients. The data on exposures including ferritin, serum iron, transferrin saturation (TSAT), and total iron-binding capacity (TIBC) were obtained from a genome-wide association study (GWAS). The outcomes were diabetic nephropathy, Type 1 diabetes mellitus (T1DM) with renal complications, Type 2 diabetes mellitus (T2DM) with renal complications, estimated glomerular filtration rate (creatinine) (eGFRcrea) in diabetes mellitus, and urinary albumin-to-creatinine ratio (UACR) in diabetes mellitus.
View Article and Find Full Text PDFJCEM Case Rep
October 2025
Servicio de Endocrinología y Nutrición, Hospital Universitario Clínico San Carlos, Madrid 28040, Spain.
This case report describes a 25-year-old woman with type 1 diabetes mellitus (T1DM) and autoimmune thyroid disease (AITD) who developed Addison disease (AD). The diagnosis was suspected due to a significant decrease in insulin requirement and recurrent hypoglycemia despite adjustments in insulin pump therapy. The patient exhibited typical clinical features of AD, including hyperpigmentation and electrolyte imbalances.
View Article and Find Full Text PDFRegen Ther
December 2025
Department of Ophthalmology, Affiliated Zhongshan Hospital Dalian University, Dalian, 116001, Liaoning Province, China.
Objective: It aimed to thoroughly analyze the promotive outcome of Resolvin D1 (RvD1) on the repair of corneal epithelium (CE) damage in diabetes mellitus (DM) mice and its molecular mechanisms.
Methods: 27 male C57BL/6J mice were selected. Type 1 diabetes mellitus(T1DM) mice models were prepared by streptozotocin (STZ) intraperitoneal injection (IPI), and central CE scraping was performed on all mice.
Int J Cancer
September 2025
Tampere Center for Child, Adolescent, Maternal Health Research and Tays Cancer Center, Tampere University and Tampere University Hospital, Tampere, Finland.
Etiology of childhood acute leukemia is largely unknown, though environmental factors and infection-related immune responses may contribute. Type 1 diabetes mellitus (T1DM), an autoimmune disease also with onset primarily in childhood, shares risk factors with leukemia, including childhood infection patterns. Epidemiological evidence suggests a link between T1DM and leukemia, but the extent of this association remains unclear.
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