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Article Abstract
The distribution of saline-alkali water is extensive and is increasing globally each year. Fully utilizing saline-alkali water for aquaculture can help alleviate the scarcity of freshwater resources in global fisheries. As a major economic fish species, the largemouth bass () holds significant potential for aquaculture in saline-alkali water. In the present study, we evaluated its tolerance to different salinities (0 ppt, 6 ppt, 9 ppt, 12 ppt, 15 ppt, and 18 ppt) and investigated tissue pathology, serum biochemical indicators, enzyme activities of osmolality and antioxidant, and the relative expression of Na-K-2Cl 1a cotransporter () under different saline stress (0 ppt, 6 ppt, 9 ppt, and 12 ppt). The largemouth bass 96 h mortality rate increased with increasing salinity, and the LC for 96 h was 14.28 ppt based on the mortality results. High salinity group (12 ppt) caused gill and intestinal damage, including necrosis and cell shedding, while 6 ppt had no adverse effects, and the 9 ppt between the two salinities showed an adaptive change histologically. Serum osmolality, Na, Cl, and cortisol levels of the high salinity group were significantly higher than of the low salinities ( < 0.05). Similarly, Na/K-ATPase (NKA), Ca-Mg-ATPase (CMA), and superoxide dismutase (SOD) activities of 12 ppt peaked at 24 h (15.7 U/mgprot, 11.5 U/mgprot, and 243 U/mgprot), which is significantly different compared to the other three groups ( < 0.05). The expression of was significantly upregulated at 9 ppt and 12 ppt, suggesting its role in osmoregulation. Furthermore, the expression of in the gill is 2-4 times higher than that in the intestine. These results suggested that largemouth bass can be cultured at 6 ppt and selectively bred for tolerance at 9 ppt. NKA activity, cortisol levels, and expression can be used as a marker of salinity suitability. These findings provide insight into the adaptive mechanisms underlying the physiological responses to acute salinity stress and will contribute to improving aquaculture in saline waters.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12028043 | PMC |
| http://dx.doi.org/10.3390/ijms26083847 | DOI Listing |
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