Dual-tracer PET in prostate synovial sarcoma: discordant FDG and PSMA uptake with metastatic patterns.

Eur J Nucl Med Mol Imaging

Department of Nuclear Medicine, Institute of Clinical Nuclear Medicine, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China.

Published: April 2025


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Article Abstract

We present the case of primary prostatic synovial sarcoma exhibiting discordant tracer avidity on [F]-FDG PET/MRI and [F]-PSMA PET/CT-a metabolic divergence suggesting clonal evolution and potential eligibility for PSMA-targeted radioligand therapy to combat poor survival in this rare sarcoma subtype.

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http://dx.doi.org/10.1007/s00259-025-07303-1DOI Listing

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