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Nitric oxide (NO) is a widely recognized signaling molecule found across various organisms, yet its specific effects on fungal growth and development under anaerobic conditions remain underexplored. This study investigates how NO influences the growth and development of 20R-7-F01 under anaerobic environments. The results demonstrated an increase in endogenous NO levels during mycelial growth and basidiospore germination. The addition of cPTIO, a NO scavenger, inhibited mycelial growth, delayed basidiospore germination, and reduced the expression of genes involved in basidiospore germination, highlighting the critical role of NO in fungal growth and development. On the other hand, exogenous NO supplementation accelerated mycelial growth and facilitated the formation of primordia, suggesting NO's potential as a key regulator of fungal development. These findings deepen our understanding of NO's contribution to fungal growth in anaerobic conditions and offer new perspectives on its role as a signaling molecule in the development of communities, shedding light on the metabolic regulation of anaerobic microorganisms.
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http://dx.doi.org/10.3390/microorganisms13040887 | DOI Listing |
Sci Prog
September 2025
Shenzhen University Sixth Affiliated Hospital, Shenzhen Nanshan People's Hospital, Shenzhen, China.
Colorectal cancer ranks among the most prevalent and lethal malignant tumors globally. Historically, the incidence of colorectal cancer in China has been lower than that in developed European and American countries; however, recent trends indicate a rising incidence due to changes in dietary patterns and lifestyle. Lipids serve critical roles in human physiology, such as energy provision, cell membrane formation, signaling molecule function, and hormone synthesis.
View Article and Find Full Text PDFInt J Surg
September 2025
Department of Gynecology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China.
Background: Ovarian cancer remains the most lethal gynecological cancer, with fewer than 50% of patients surviving more than five years after diagnosis. This study aimed to analyze the global epidemiological trends of ovarian cancer from 1990 to 2021 and also project its prevalence to 2050, providing insights into these evolving patterns and helping health policymakers use healthcare resources more effectively.
Methods: This study comprehensively analyzes the original data related to ovarian cancer from the GBD 2021 database, employing a variety of methods including descriptive analysis, correlation analysis, age-period-cohort (APC) analysis, decomposition analysis, predictive analysis, frontier analysis, and health inequality analysis.
Vet Res Commun
September 2025
Department of Physiology, Faculty of Veterinary Medicine, Cairo University, PO 11221, Giza, Egypt.
This comprehensive review examines the versatile applications and effects of Moringa oleifera across multiple fish species in aquaculture systems amid growing challenges of rising feed costs and antimicrobial resistance. M. oleifera, commonly called the Miracle tree, contains an exceptional nutritional profile with high protein content (22.
View Article and Find Full Text PDFJ Urban Health
September 2025
School of Architecture and Design, Harbin Institute of Technology, Harbin, 150001, China.
Street-level environments play a vital role in children's development by promoting their physical activity, cognitive growth, and overall development. This study systematically reviews the measurement tools available to assess street environments according to children's needs. This systematic review was conducted according to the PRISMA-COSMIN guidelines.
View Article and Find Full Text PDFBiotechnol Lett
September 2025
Unit of Microbiology and Immunology, Vector Control Research Centre, Indian Council of Medical Research, Department of Health Research, Ministry of Health and Family Welfare, Puducherry, 605006, India.
Effective mosquito control is essential for reducing the transmission of vector-borne diseases. This study focuses on the comprehensive characterization of mosquitocidal toxins produced by Bacillus thuringiensis serovar israelensis (Bti) VCRC B646 and the associated insecticidal genes. The bacterium was cultured, and the spore-crystal complex was purified to identify the mosquitocidal proteins.
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