Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Purpose: To assess the effect of COVID-19 related maternal psychological stress (MS) in the first trimester of pregnancy on non-syndromic orofacial-clefts (NSOFCs).
Methods: This retrospective case-control cross-sectional study included infants who were born during the COVID-19 pandemic. Sample size was determined based on differences in MS and their effect on clefts etiology. Infants were divided into two groups: cases (with NSOFCs) and controls (healthy); two controls were selected for each case, matched by gender and residence. Data was collected from mothers through phone-based questionnaires which consisted of three parts: demographics, risk factors, and maternal stress using the Life Events Questionnaire (LEQ) and Fear of COVID-19 Scale (FCV-19S). Descriptive statistics, correlations and logistic regression were done, level of significance was set at (P ≤ 0.05).
Results: The final sample included 192 infants: (64 cases, 128 controls), mostly females, born full-term, with normal weight (55.2%, 72.9%, and 62.5%, respectively). Mothers ages were 19-41 years. Prevalence of NSOFCs was 1.41 birth per 1000 live births. The LEQ showed that changing residence (P = 0.012) and overall stress (P = 0.019) were significant factors for mothers in both groups. Regression analysis showed that low gestational age of the infant (P = 0.009), lack of folic acid intake during the first trimester (P = 0.037), parental consanguinity (P = 0.019) and maternal stress due to COVID-19 pandemic (P = 0.039) were risk factors for NSOFCs.
Conclusion: Despite limitations of reliance on self-reported MS, this study suggests that maternal stress is a risk factor for NSOFCs. More studies need to be conducted addressing MS during prenatal and perinatal periods.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s40368-025-01035-4 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effectiveness of Medical Nutrition Therapy in the Management of Patients with Obesity and Endometriosis: from the Mediterranean Diet To the Ketogenic Diet, Through Supplementation. The Role of the Nutritionist in Clinical Management.
Curr Obes Rep
September 2025
Department of Medicine, Division of Endocrinology, University of Arizona, Tucson, AZ, USA.
Purpose Of The Review: This review aimed to summarize current evidence on the effectiveness of medical nutrition therapy (MNT) in the management of obesity and endometriosis, with a focus on dietary patterns such as the Mediterranean and Ketogenic diets, as well as nutritional supplementation. Additionally, it highlights the central role of the clinical nutritionist in implementing individualized, evidence-based interventions within multidisciplinary care.
Recent Findings: Although the literature reports the existence of an inverse relationship between risk of endometriosis and body mass index, clinical evidence jointly reports that a condition of obesity is associated with greater disease severity.
How Healthcare Provider Characteristics Affect Their Attitudes and Skills in Involving Families in Caring for Small and Sick Newborns Throughout the Perinatal Period.
SAGE Open Nurs
September 2025
Department of Family and Community Health, Fred N. Binka School of Public Health, University of Health and Allied Sciences, Ho, Ghana.
Introduction: Healthcare providers (HCPs) are essential in providing care and working with families with small and sick newborns throughout the perinatal care continuum. While clinical experience, education, and training influence HCPs' attitudes and skills regarding family involvement in care, the specific factors affecting Ghanaian HCPs remain unclear.
Objectives: To identify HCPs' characteristics that influence their attitudes and self-perceived practice skills toward involving families in the perinatal care continuum for small and sick newborns.
An exploration of perspective of knowledge, attitude and help seeking behaviour in pregnant women and their families towards psychiatric ailments in a primary health care setting in South India - A cross sectional study.
Indian J Psychiatry
August 2025
Department of Psychiatry, The Oxford Medical College, Hospital and Research Centre, Bangalore, Karnataka, India.
Background: Mental illness, often linked to ignorance and superstitions, significantly impacts women's mental health, particularly during pregnancy-marked by significant physical, emotional, and psychological changes. Prenatal mental health screening face challenges like stigma and lack of standardized protocols, while family support is essential reducing stress and enhancing well-being.
Aim: To assess knowledge, attitude and help seeking behaviors towards mental ailments among pregnant women and their families visiting primary health centers (PHCs).
The role of amniotic epithelial cells in preterm birth: mechanisms and clinical implications.
Front Cell Dev Biol
August 2025
Department of Obstetrics, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Preterm birth (PTB), defined as delivery before 37 weeks of gestation, poses a significant global health challenge. This review comprehensively examines the multifaceted role of amnion epithelial cells (AECs) in normal labor induction and preterm birth. AECs, derived from the amniotic ectoderm, exhibit paracrine effects, low immunogenicity, and non-tumorigenicity properties.
View Article and Find Full Text PDFBreastfeeding Continuation at One Month Postpartum Among Women in Treatment for Opioid Use Disorder Who Initiated Breastfeeding: Prevalence and Determinants.
Womens Health Rep (New Rochelle)
August 2025
College of Nursing, Thomas Jefferson University, Phila, Pennsylvania, USA.
Objective: To describe breastfeeding behaviors and determinants in the 1-month postdelivery period among women in treatment for opioid use disorder.
Study Design: Participants completed one questionnaire during pregnancy and one questionnaire at 1 month postpartum. Those who reported on the postpartum questionnaire that they had initiated breastfeeding were included in this analysis ( = 31).