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BackgroundDialysis is a very complex treatment that is received by around 3 million people annually. Around 10% of the death cases in the presence of the dialysis machine were due to the technical errors of dialysis devices. One of the ways to maintain dialysis devices is by using machine learning and predictive maintenance in order to reduce the risk of patient's death, costs of repairs and provide a higher quality treatment.ObjectivePrediction of dialysis machine performance status and errors using regression models.MethodThe methodology includes seven steps: data collection, processing, model selection, training, evaluation, fine-tuning, and prediction. After preprocessing 1034 measurements, twelve machine learning models were trained to predict dialysis machine performance, and temperature and conductivity error values.ResultsEach model was trained 100 times on different splits of the dataset (80% training, 10% testing, 10% evaluation). Logistic regression achieved the highest accuracy in predicting dialysis machine performance. For temperature predictions, Lasso regression had the lowest MSE on training data (0.0058), while Linear regression showed the highest R² (0.59). For conductivity predictions, Lasso regression provided the lowest MSE (0.134), with Decision tree achieving the highest R² (0.2036). SVM attained the lowest MSE on testing dataset, with 0.0055 for temperature and 0.1369 for conductivity.ConclusionThe results of this study demonstrate that clinical engineering (CE) and health technology management (HTM) departments in healthcare institutions can benefit from proposed automated systems for advanced management of dialysis machines.
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http://dx.doi.org/10.1177/09287329251328815 | DOI Listing |
Indian J Nephrol
September 2024
Department of Nephrology, Regional Institute of Medical Sciences, Imphal, Manipur, India.
Background: Chronic kidney disease patients on maintenance hemodialysis have multiple co-morbidities and high risk of infections. This study was conducted to assess the idea and practice of infection control measures in dialysis units in northeast India.
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Front Oncol
August 2025
Department of Nephrology, Dialysis and Internal Medicine, Medical University of Warsaw, Warsaw, Poland.
Messenger ribonucleic acid (mRNA) technology is a promising platform for cancer immunotherapy. Unlike traditional vaccines that prevent infectious diseases, mRNA's role in oncology is to stimulate or enhance the immune response against tumor antigens. This review provides an overview of mRNA's historical development, from its discovery in 1961 to recent clinical trials and Nobel Prize-winning breakthroughs.
View Article and Find Full Text PDFBiomed Eng Online
August 2025
College of Chemistry and Life Science, Beijing University of Technology, Beijing, 100124, China.
Background: Coronary artery calcification (CAC) represents a major cardiovascular risk in patients with end-stage renal disease (ESRD) undergoing hemodialysis. Given that radial artery pulse waveforms can reflect vascular status, this study aimed to evaluate their utility in the non-invasive assessment of CAC severity.
Methods: 58 patients with ESRD undergoing hemodialysis were enrolled.
Vaccines (Basel)
July 2025
Department of Medicine, Gødstrup Hospital, 7400 Herning, Denmark.
Background: Kidney transplant recipients (KTRs) exhibit a significantly diminished immune response to Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) vaccines compared with the general population, primarily due to ongoing immunosuppressive therapy. This study evaluated the immunogenicity of a third SARS-CoV-2 mRNA vaccine dose in KTRs and assessed the association between antibody response and protection against SARS-CoV-2 breakthrough infection. Additionally, the clinical and immunological correlates of post-vaccination SARS-CoV-2 infection were examined.
View Article and Find Full Text PDFWorld J Transplant
September 2025
Division of Cardiac Surgery, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43201, United States.
Background: Traditional limitations of cold static storage (CSS) on ice at 4 °C during lung transplantation have necessitated limiting cold ischemic time (CIT) to 4-6 hours. lung perfusion (EVLP) can extend this preservation time through the suspension of CIT and normothermic perfusion. As we continue to further expand the donor pool in all aspects of lung transplantation, teams are frequently traveling further distances to procure organs.
View Article and Find Full Text PDF