Article Synopsis
- The study explored how maternal glucose levels affect the composition and volume of breast milk in mothers with type 1 diabetes (T1D).
- Researchers collected midfeed breast milk samples from 11 mothers with T1D and compared them with samples from five mothers without T1D.
- Results indicated that higher maternal glucose levels were linked to increased glucose and fructose in the breast milk, while the volume consumed by infants wasn't related to maternal glucose.
- Additionally, mothers with T1D had higher levels of breast milk glucose and leptin compared to those without T1D.
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Article Abstract
Objective: To examine relationships between maternal glucose and breast milk composition and volume ingested by infants of mothers with type 1 diabetes (T1D), and to compare breast milk composition in women with and without T1D.
Research Design And Methods: Midfeed breast milk samples were collected from 11 mothers with T1D. Maternal continuous glucose monitoring data were correlated with breast milk composition and volume ingested. Breast milk composition was compared between the women with T1D and five without T1D.
Results: Forty-seven breast milk samples from mothers with T1D were analyzed. Maternal glucose 90-120 min before breastfeeding correlated with breast milk glucose and fructose but not with lactose, protein, fatty acids, leptin, or volume consumed. Breast milk leptin correlated with volume of breast milk consumed (r = 0.394; P = 0.008). Higher breast milk glucose (1.0 ± 0.3 vs. 0.7 ± 0.3 mg/mL) and leptin (463.6 ± 480.0 vs. 114.4 ± 68.6 pg/mL) were found in women with versus without T1D.
Conclusions: Maternal glucose is associated with breast milk glucose and fructose in women with T1D but not with volume of breast milk consumed.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12281972 | PMC |
| http://dx.doi.org/10.2337/dc25-0096 | DOI Listing |
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