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[This corrects the article DOI: 10.1021/acsomega.1c04999.].
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http://dx.doi.org/10.1021/acsomega.5c01409 | DOI Listing |
Mol Divers
September 2025
Information Technology and Computing Applications, Vignan's Foundation for Science, Technology and Research (Deemed to be University), Guntur, India.
Acta Neurochir (Wien)
September 2025
Department of Neurosurgery, Istinye University, Istanbul, Turkey.
Background: Recent studies suggest that large language models (LLMs) such as ChatGPT are useful tools for medical students or residents when preparing for examinations. These studies, especially those conducted with multiple-choice questions, emphasize that the level of knowledge and response consistency of the LLMs are generally acceptable; however, further optimization is needed in areas such as case discussion, interpretation, and language proficiency. Therefore, this study aimed to evaluate the performance of six distinct LLMs for Turkish and English neurosurgery multiple-choice questions and assess their accuracy and consistency in a specialized medical context.
View Article and Find Full Text PDFAnesthesiology
October 2025
Department of Anaesthesia and Perioperative Medicine, Guy's and St Thomas' National Health Service Foundation Trust, London, United Kingdom; Centre for Human and Applied Physiological Sciences, King's College London, London, United Kingdom.
The application of cricoid force remains controversial in modern practice. This review critically assesses the anatomic, physiologic, and contemporary clinical evidence of cricoid force application. There may be a sound anatomic basis to cricoid force application, involving occlusion of the postcricoid hypopharynx, but the physiologic basis is uncertain.
View Article and Find Full Text PDFJ Agric Food Chem
September 2025
School of Chemical Engineering and Technology, Zhengzhou University, Zhengzhou 450001, China.
d-Amino acid oxidase from (DAAO) is valuable for pharmaceutical and chemical synthesis due to its high enantioselectivity, but its poor thermostability limits extensive application. This study proposed a synergistic strategy of "sequence consensus design coupled with structure modification" to enhance DAAO thermostability. Through homologous sequence analysis and greedy algorithm-based optimization, a triple mutant M3 (S18T/V7I/Y132F) was obtained, showing a 3.
View Article and Find Full Text PDFPsychogeriatrics
September 2025
Shanghai University of Medicine and Health Sciences, School of Nursing and Health Management, Shanghai, China.
Background: Cognitive frailty (CF), characterised by the co-occurrence of physical frailty and mild cognitive impairment, poses significant risks for adverse health outcomes in community-dwelling older adults, yet effective prediction tools remain limited.
Objective: This study aimed to develop and validate a nomogram model for predicting CF risk in community-dwelling older adults based on multidimensional mental and physical functional markers.
Methods: A cross-sectional analysis included 481 participants (mean age 69.