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The Green View Index (GVI) is utilized to evaluate urban street value and ecosystem services and to gauge public perceptions of street greening. This study investigates the spatial heterogeneity of the GVI and its influencing factors in Yuzhong District, Chongqing, a mountainous city in China. Deep learning algorithms were employed to calculate the green visibility of street view images, and Geographic Weighted Regression (GWR) and the Optimal Parameter-Based Geodetector (OPGD) were utilized to analyze the relationships between GVI and factors such as road physical attributes, the Normalized Difference Vegetation Index (NDVI), and topographic features. The results indicate that: (1) In Yuzhong District, 58.9% of streets have a GVI within a low to moderate range, suggesting room for improvement. Higher GVI levels are generally associated with elevated Digital Elevation Models (DEM), while slope, aspect, and terrain undulation have relatively minor overall impacts on GVI. (2) The GVI is highest in the western regions and lowest in the eastern regions, with streets along the riversides exhibiting lower GVI levels. (3) GWR analysis reveals that road type and NDVI significantly influence the GVI. Higher DEM values promote increased GVI, whereas high road density suppresses it. (4) The interaction between influencing factors drives the differentiated distribution of GVI within the study area. The interaction effects between Road type, NDVI, and DEM are particularly notable among these.
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http://dx.doi.org/10.1038/s41598-025-97946-9 | DOI Listing |
Pediatr Surg Int
September 2025
Department of Urology Children's Hospital, Chongqing Medical University, Room 806, Kejiao Building (NO.6), No.136, Zhongshan 2nd Road, Yuzhong District, Chongqing, 400014, China.
Cryptorchidism is one of the most common reproductive malformations in children, and the timing of surgery significantly impacts fertility and the risk of testicular cancer. Although international guidelines currently recommend testicular fixation within 6-18 months to improve prognosis, many children worldwide undergo surgery later than the recommended age. Delays in surgery are particularly significant in developing countries.
View Article and Find Full Text PDFBrief Bioinform
August 2025
College of Pharmacy, Chongqing Medical University, No. 1 Yixueyuan Road, Yuzhong District, Chongqing 400016, P. R. China.
Drug-induced hepatotoxicity (DIH), characterized by diverse phenotypes and complex mechanisms, remains a critical challenge in drug discovery. To systematically decode this diversity and complexity, we propose a multi-dimensional computational framework integrating molecular structure analysis with disease pathogenesis exploration, focusing on drug-induced intrahepatic cholestasis (DIIC) as a representative DIH subtype. First, a graph-based modularity maximization algorithm identified DIIC risk genes, forming a DIIC module and eight disease pathogenesis clusters.
View Article and Find Full Text PDFFunct Integr Genomics
September 2025
Department of Otolaryngology-Head and Neck Surgery, Maternal and Child Health Hospital of Hubei Province, NO.745 Wuluo Road, Hongshan District, Wuhan, 430070, Hubei Province, China.
Background: Head and neck squamous cell carcinoma (HNSCC) stands as a significant global health concern, marked by its substantial impact on both morbidity and mortality rates. Although previous studies have suggested that circular RNAs (circRNAs) may influence HNSCC progression, the underlying mechanisms remain largely unclear.
Methods: In this study, we first used quantitative real-time polymerase chain reaction (qRT-PCR) to measure the expression levels of circSHPRH in HNSCC tissues and cell lines.
Curr Neurovasc Res
August 2025
The Second Affiliated Hospital of Chongqing Medical University, China, No. 76, Linjiang Road, Yuzhong District, Chongqing, China.
Introduction: This study aims to investigate the effect of the serum Total Cholesterol (TC) to High-Density Lipoprotein cholesterol (HDL) ratio (T/H ratio) on Hemorrhagic Transformation (HT) after Intravenous Thrombolysis (IVT) in patients with Acute Cerebral Infarction (ACI).
Methods: Patients with ACI who received alteplase were enrolled. Subgroups were classified based on the occurrence of hemorrhagic transformation (HT) after intravenous thrombolysis (IVT), whether tirofiban was coadministered, and their 90-day prognosis.
Int J Clin Pharm
September 2025
Department of Pharmacy, The Third Affiliated Hospital of Chongqing Medical University, 1 Shuanghu Branch Rd, Yubei District, Chongqing, 401120, People's Republic of China.
Introduction: Venous thromboembolism (VTE) is a common and preventable complication in orthopedic surgery, yet adherence to prophylaxis guidelines remains suboptimal. A pharmacist-led anticoagulation care model based on the Pharmacist Early Active Consultation (PEAC) framework may enhance the quality and safety of VTE prevention in surgical patients.
Aim: This study aimed to evaluate the impact of a pharmacist-led Venous Thromboembolism Clinical Pharmaceutical Care (VTE-CPC) model, derived from the PEAC framework, on VTE prevention and anticoagulation quality in orthopedic surgery patients.