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In this paper, polarization diversity is integrated into a 3 × 3 coupler-based passive demodulation system for the first time to mitigate polarization-induced fading (PIF) in interferometric fiber-optic sensors (IFOSs). This study investigates the impact of single-mode fiber at the receiving end of a polarization diversity receiver (PDR) on signal demodulation. This impact causes variations in the fixed phase difference introduced by the 3 × 3 coupler in passive systems, leading to demodulation failure. To overcome this limitation, what we believe is a new method is proposed, including an automatic selection algorithm, an ellipse fitting algorithm for phase difference, and an improved arctangent algorithm to demodulate disturbance signals correctly. In theory, the approach introduced in this paper can also be effectively utilized in other IFOS systems to mitigate polarization fading. Experimental results demonstrate that the proposed system reduces the failure probability due to PIF to 6/55 of that in the traditional system and achieves a maximum localization error of less than 17 m over a 40 km sensing range. This advancement significantly enhances the reliability and applicability of passive demodulation systems in scenarios requiring long-term stable detection, such as pipeline integrity monitoring and perimeter security.
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http://dx.doi.org/10.1364/OE.550507 | DOI Listing |
Proc Natl Acad Sci U S A
September 2025
Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India.
Agonist-induced interaction of G protein-coupled receptors (GPCRs) with β-arrestins (βarrs) is a critical mechanism that regulates the spatiotemporal pattern of receptor localization and signaling. While the underlying mechanism governing GPCR-βarr interaction is primarily conserved and involves receptor activation and phosphorylation, there are several examples of receptor-specific fine-tuning of βarr-mediated functional outcomes. Considering the key contribution of conformational plasticity of βarrs in driving receptor-specific functional responses, it is important to develop novel sensors capable of reporting distinct βarr conformations in cellular context.
View Article and Find Full Text PDFJ Comput Neurosci
September 2025
School of Electrical and Information Engineering, Tianjin University, Tianjin, 300072, China.
Transcranial alternating current stimulation (tACS) enables non-invasive modulation of brain activity, holding promise for cognitive research and clinical applications. However, it remains unclear how the spiking activity of cortical neurons is modulated by specific electric field (E-field) distributions. Here, we use a multi-scale computational framework that integrates an anatomically accurate head model with morphologically realistic neuron models to simulate the responses of layer 5 pyramidal cells (L5 PCs) to the E-fields generated by conventional M1-SO tACS.
View Article and Find Full Text PDFMar Life Sci Technol
August 2025
School of Ocean Sciences, China University of Geosciences (Beijing), Beijing, 100083 China.
Unlabelled: Marinisomatota (formerly recognized as Marinimicrobia, Marine Group A, and SAR406) are ubiquitous and abundant in marine environments, traditionally characterized as heterotrophic microorganisms. However, certain members of Marinisomatota have demonstrated the capacity to harness light for carbon dioxide fixation and the synthesis of organic compounds, thriving in the translucent zone or transitioning between the translucent and aphotic layers. The metabolic strategies driving the shift in trophic behaviors, and the factors influencing these transitions, remain largely unexplored.
View Article and Find Full Text PDFMar Life Sci Technol
August 2025
Institute of Marine and Environmental Technology, University of Maryland Center for Environmental Science, Baltimore, MD 21202 USA.
Tiny unicellular cyanobacteria or picocyanobacteria (0.5-3 µm) are important due to their ecological significance. Chesapeake Bay is a temperate estuary that contains abundant and diverse picocyanobacteria.
View Article and Find Full Text PDFMar Life Sci Technol
August 2025
State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240 China.
Unlabelled: Traditional cultivation methods with defined growth media can only isolate and cultivate a small number of microbes. However, much higher microbial diversity has been detected by cultivation-independent tools from a range of natural ecosystems. These represent a large unexplored pool of potentially novel taxa.
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