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http://dx.doi.org/10.1016/j.biopsych.2025.03.023 | DOI Listing |
Biol Psychiatry Cogn Neurosci Neuroimaging
September 2025
School of Psychology, The University of Queensland, Brisbane, Queensland, Australia; Centre for Advanced Imaging/Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, Queensland, Australia. Electronic address:
Biol Psychiatry Cogn Neurosci Neuroimaging
September 2025
Department of Psychiatry, University of California, Davis, Sacramento, California. Electronic address:
Biol Psychiatry Cogn Neurosci Neuroimaging
September 2025
University of Illinois at Chicago, Department of Psychiatry. Electronic address:
Background: Late-life depression (LLD) is associated with negative outcomes including high rates of recurrence and cognitive decline. However, the neurobiological changes influencing such outcomes in LLD are not well understood. Disequilibrium in large-scale brain networks may contribute to LLD-related cognitive decline.
View Article and Find Full Text PDFSchizophr Res
September 2025
Department of Psychiatry, UT Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390, USA. Electronic address:
Alterations in hippocampal structure and function are established in schizophrenia. However, the specific patterns of hippocampal activity along the schizophrenia course remain unknown. Eighty-five study participants [34 schizophrenia probands (SZ), 32 first-degree relatives (REL), 19 healthy controls (HC)] underwent 3Tesla ultra-high resolution brain MRI (Vascular Space Occupancy); relative cerebral blood volume (rCBV)-an index of regional activity-was estimated across hippocampal subfields: dentate gyrus (DG), CA3, CA1, and subiculum (SUB).
View Article and Find Full Text PDFNpj Ment Health Res
September 2025
Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin (Campus Charité Mitte), Berlin, Germany.
Loneliness is a growing global health issue, yet real-time assessments of its objective risk and protective factors are limited. This study identifies momentary and daily predictors using digital phenotyping and temporal analysis. Analyzing 12788 momentary observations from social mobile sensing and actigraphy, we examined how they impact loneliness on average (between-person) and in daily fluctuations (within-person).
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