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Background: Efforts to improve maternal health have focused on measuring health and nutrition service coverage. Despite improvements in service coverage, maternal mortality rates remain high. This suggests that coverage indicators alone do not fully capture the quality of care and may overestimate the health benefits of a service. Effective coverage (EC) cascades have been proposed as an approach to capture service quality within population-based coverage measures, but the proposed maternal health EC cascades have not been operationalised. This study aims to operationalise the effective coverage cascades for antenatal care (ANC) and maternal nutrition services using existing data from low- and middle-income countries (LMICs).
Methods: We used household surveys and health facility assessments from seven LMICs to estimate EC cascades for ANC and maternal nutrition services provided during ANC visits. We developed theoretical coverage cascades, defined health facility readiness and provision/experience of care scores and linked the facility-based scores to household survey data based on geographic domain and facility type. We then estimated the coverage cascade steps for each service by country.
Results: Service contact coverage for at least one ANC visit (ANC1) was high, ranging from 80% in Bangladesh to 99% in Sierra Leone. However, there was a substantial drop in coverage from service contact to readiness-adjusted coverage, and a further drop to quality-adjusted coverage for all countries. For ANC1, from service contact to quality-adjusted coverage, there was an average net decline of 52 percentage points. For ANC1 maternal nutrition services, there was an average net decline of 48 percentage points from service contact to quality-adjusted coverage. This pattern persisted across cascades. Further exploration revealed that gaps in service readiness including lack of provider training, and gaps in provision/experience of care such as limited nutrition counselling were core contributors to the drops in coverage observed.
Conclusions: The cascade approach provided useful summary measures that identified major barriers to EC. However, detailed measures underlying the steps of the cascade are likely needed to support evidence-based decision-making with more actionable information. This analysis highlights the importance of understanding bottlenecks in achieving health outcomes and the inter-connectedness of service access and service quality to improve health in LMICs.
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http://dx.doi.org/10.7189/jogh.15.04041 | DOI Listing |
Prev Med
September 2025
Department of Pharmacy, Taoyuan General Hospital, Ministry of Health and Welfare, No. 1492, Zhongshan Rd., Taoyuan 33004, Taiwan. Electronic address:
Objective: Middle-aged and older adults living with HIV in the Western Pacific Region (WPR) are experiencing accelerated aging and a rising burden of non-communicable disease (NCD)-related comorbidities. This systematic review and meta-analysis aimed to assess the burden of major NCDs-measured by prevalence, incidence, and mortality-among people living with HIV(PLWH) aged 40 years and older, in comparison to their HIV-negative counterparts.
Methods: A comprehensive literature search was conducted across Medline (1966-), Embase (1974-), Cochrane Library (1996-), Epistemonikos (established in 2012, with retrospective coverage), and Web of Science (1900-) to identify relevant studies published up to May 9, 2025.
J Colloid Interface Sci
September 2025
School of Materials Science and Engineering, Taizhou University, Taizhou 318000, China. Electronic address:
The sequential preparation of perovskite solar cells (PSCs) has received widespread concern for its use in large-scale perovskite modules and perovskite/silicon tandem solar cells. However, the instability of the PbI precursor solution and the incomplete reaction of ammonium salts hinder the industrialization of PSCs. Here, by introducing phthalamide (PA) into PbI solution, the carbonyl oxygen of PA molecules undergoes a bidentate coordination reaction with Pb to form an octahedral coordination structure, and the nitrogen atom in the -NH group exhibits weakly acidic properties due to the conjugation effect.
View Article and Find Full Text PDFWaste Manag
September 2025
Department of Earth and Environment Sciences, St. Francis Xavier University, Antigonish, Canada.
We measured emissions from ten landfills using mobile surveys and Surface Emission Monitoring (SEM) to determine what fraction of emissions can be identified by SEM surveys. SEM is commonly used for regulatory compliance and leak detection at specific locations. However, evolving regulations emphasize the need to manage methane emissions from the entire landfill site, and the suitability of SEM for this objective remains unclear.
View Article and Find Full Text PDFHealth Expect
October 2025
Murdoch Children's Research Institute, Parkville, Victoria, Australia.
Introduction: Despite high coverage of routine childhood vaccines, uptake of the human papillomavirus (HPV) vaccine in the Pacific Island nation of Tonga has been slow. Culturally appropriate communication resources on the importance, safety, and effectiveness of the HPV vaccine are critical to support acceptance and uptake. To develop these resources, it is important to understand what people want to know.
View Article and Find Full Text PDFMol Biotechnol
September 2025
NSW Department of Primary Industries, Elizabeth Macarthur Agricultural Institute, Menangle, NSW, 2568, Australia.
In agriculture, biosecurity, and human health, the rapid and accurate detection of pathogens and pests is crucial. Our study investigates the sensitivity and practicality of six guide RNA (gRNA) production methods for use in Nanopore Cas9-targeted sequencing (nCATS), focusing on their implications for multiplexed pathogen and pest detection. Each production method generated a library of eight gRNAs capable of excising ~ 1.
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