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http://dx.doi.org/10.1111/ceo.14536 | DOI Listing |
J Ayurveda Integr Med
September 2025
Research Officer (Siddha), Siddha Regional Research Institute, Puducherry, India.
Background: Psoriasis is a chronic skin disorder with a substantial global burden, affecting over 100 million people worldwide. Conventional treatments, including topical and systemic therapies, have their own limitations and side effects. Siddha medicine, deeply rooted with comprehensive principles, offers an alternative approach in Psoriasis management.
View Article and Find Full Text PDFJ Ethnopharmacol
September 2025
Department of Chemistry, School of Science, China Pharmaceutical University, Nanjing, 211198, P. R. China; Tibetan Medicine Research Institute, University of Tibetan Medicine, Tibet 850000, P. R. China. Electronic address:
Ethnopharmacological Relevance: Lamiophlomis rotata (Benth.)Kudo(L. rotata), known in China as Duyiwei (DYW), is a well-known traditional Tibetan medicine.
View Article and Find Full Text PDFBiochem Biophys Res Commun
September 2025
Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; A∗STAR Skin Research Labs (A∗SRL), Skin Research Institute of Singapore (SRIS), Singapore Immunology Network (SIgN), Agency for Science, Technology, and Research (A∗STAR), 8A Biomedical Grove, IMMUNOS Buildi
Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by eczematous lesions, intense itching, and compromised skin barrier function. Despite the advent of new therapeutics, many individuals still face insufficient disease control, high costs, and relapse. Protease-activated receptor 2 (PAR-2), overexpressed in AD lesions, plays a central role in promoting inflammation, itch, and alterations in epidermal homeostasis.
View Article and Find Full Text PDFJ Cosmet Dermatol
September 2025
Cosmetic Laser Dermatology, San Diego, California, USA.
Background: With the rise of regenerative medicine and geroscience, translational research has shifted focus from lifespan to healthspan-years lived in good health. Applied to aesthetic medicine, the authors introduce the concept of "skinspan," to both describe the period during which skin maintains a youthful, healthy appearance, and additionally to serve as a tool for the cosmetic consult.
Aims: The aim of this comprehensive review is to illuminate "skinspan" as a framework for guiding long-term skin health.
J Drugs Dermatol
September 2025
Background: Alopecia universalis (AU) is the most severe form of alopecia areata (AA), characterized by complete scalp and body hair loss. While post-COVID-19 hair loss is often attributed to telogen effluvium (TE), emerging evidence suggests that COVID-19 may also trigger AU through immune dysregulation, particularly via interferon-gamma (IFN-γ)-mediated inflammation. The chronic and relapsing nature of AU raises challenges in long-term disease management, particularly regarding treatment duration and relapse prevention.
View Article and Find Full Text PDF