Biodegradation of the Fungicide Picoxystrobin by sp. H-9 and Detoxification Mechanism as Indicated by the Microalgae .

Picoxystrobin is widely used in agriculture, causing residual contamination of habitats and ecotoxicity. In this study, a picoxystrobin-degrading strain H-9 was isolated and identified as sp. It can rapidly degrade four strobilurin fungicides (picoxystrobin, trifloxystrobin, azoxystrobin, and kresoxim-methyl) to produce the corresponding SF acids and methanol via the hydrolysis of ester bonds. Picoxystrobin can significantly inhibit the growth of algal cells and the synthesis of chlorophyll in . The detoxification capacity of strain H-9 was evident as it mitigated picoxystrobin-induced growth inhibition and oxidative stress in . Strain H-9 modulated the expression of genes involved in photosynthesis, the Calvin cycle, the tricarboxylic acid cycle, glycolysis, oxidative stress, and chlorophyll synthesis, thereby alleviating picoxystrobin toxicity to . This study enhances our understanding of the detoxification mechanism of microorganisms on microalgae exposed to SF stress and provides a novel insight into the microbial remediation of SFs-contaminated environments.