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Polyphenols are secondary metabolites derived from plant metabolism and possess diverse bioactivities and health-promoting functions. They are extensively utilized in the food, pharmaceutical and cosmetic industries, and more. Recently, with the increasing focus on healthy diets, grain polyphenols have been the subject of extensive research. This review provides a comprehensive discussion of the diverse biological functions of polyphenols, which can be accomplished through the modulation of enzyme activities, signaling pathways, metabolic pathways, and the influence of membrane structure. With regard to polyphenol extraction, the review highlights novel and efficient extraction techniques. Additionally, it explores the enrichment of polyphenols through microbial action and metabolism. Finally, it offers a summary of the current status and future development potential of grain polyphenols in food and non-food fields of application. This review provides a theoretical basis for future research on grain polyphenols and a reference point for their industrialization.
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http://dx.doi.org/10.1002/mnfr.70041 | DOI Listing |
Int J Biol Macromol
September 2025
School of Grain Science and Technology, Jiangsu University of Science and Technology, Zhenjiang, 212100, China; School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, 212100, China. Electronic address:
As a naturally derived biomacromolecule, chitosan is widely utilized in food preservation. However, the chitosan derived from silkworm pupae and its application in food preservation are relatively unexplored. To obtain chitosan with enhanced preservation properties, silkworm pupae chitosan was extracted using dual-frequency ultrasound-assisted chemical and enzymatic methods, followed by a comparative analysis of their physicochemical properties, biological activity, and preservation efficacy on strawberries.
View Article and Find Full Text PDFBMC Microbiol
September 2025
Faculty of Kinesiology, University of Calgary, Calgary, AB, Canada.
Background: A plant-focused, healthy dietary pattern, such as the Mediterranean diet enriched with dietary fiber, polyphenols, and polyunsaturated fats, is well known to positively influence the gut microbiota. Conversely, a processed diet high in saturated fats and sugars negatively impacts gut diversity, potentially leading to weight gain, insulin resistance, and chronic, low-grade inflammation. Despite this understanding, the mechanisms by which the Mediterranean diet impacts the gut microbiota and its associated health benefits remain unclear.
View Article and Find Full Text PDFCarbohydr Polym
November 2025
Food & Nutritional Sciences Programme, School of Life Sciences, The Chinese University of Hong Kong, Shatin 999077, Hong Kong, China. Electronic address:
Starch-tannic acid complex is a type of resistant starch, while the influence of these complexes with different starch chain-length distributions (CLDs) on gut microbiota is unclear. Therefore, starch-tannic acid complexes were prepared from five commercial starches with diverse CLDs, and their influence on the gut microbiota was explored using in vitro fermentation with human fecal microbiota. For the first time, results showed that wheat and corn starch-tannic acid complexes significantly promoted propionate production (p < 0.
View Article and Find Full Text PDFFront Nutr
August 2025
College of Food Science and Engineering, Jilin Agricultural University, Changchun, Jilin, China.
Hyperlipidemia represents a global metabolic epidemic with increasing prevalence, profoundly associated with the etiology of cardiovascular and cerebrovascular diseases. This study investigates the therapeutic potential of two widely distributed bioactive polyphenols, Cyanidin-3-O-glucoside (C3G), catechin, and their synergistic combinatorial formation (C3G-catechin) in modulating hyperlipidemia, using complementary models (Caco-2 monolayer and Caco-2/HepG2 co-culture systems) to simulate intestinal absorption dynamics and lipid metabolic regulation. Our results reveal that the intestinal absorption efficiency follows the order of catechin > C3G-catechin > C3G, primarily mediated through passive diffusion.
View Article and Find Full Text PDFBreed Sci
April 2025
The United Graduate School of Agricultural Sciences, Iwate University, 3-18-8 Ueda, Morioka, Iwate 020-8550, Japan.
Polyphenol oxidase (PPO) is a key enzyme contributing to the time-dependent discoloration of wheat products. Developing cultivars with low PPO activity is one way to solve this problem. In this study, we focused on the gene, which has the second highest effect on grain PPO activity after the gene.
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