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Background: This study compares ultrasound and surgical findings of anatomical variations in de Quervain's disease.
Methods: Seventy-four wrists from patients with unilateral de Quervain's disease were examined through ultrasonography and surgery. Presence of intracompartment septum, abductor pollicis longus (APL) slips, and selective stenosis were verified by both methods. Two orthopedic surgeons assessed ultrasound findings for intra- and interobserver reliability.
Results: Amongst 74 participants (43 women and 31 men), 60.8% had a complete septum, 31.1% had an incomplete septum, and 8.1% had no septum; 70.3% had multi-slip APL and 66.2% had extensor pollicis brevis stenosis. Surgical and ultrasonographic findings displayed a high level of sensitivity and specificity. Intraobserver reliability was high, and interobserver reliability was substantial.
Conclusions: The study confirms ultrasonography's reliability in identifying anatomical variations in de Quervain's disease, with high sensitivity, specificity, and substantial intra- and interobserver reliability, emphasizing its usefulness in preoperative assessment and planning.
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http://dx.doi.org/10.4055/cios24127 | DOI Listing |
Orthop Traumatol Surg Res
September 2025
Ankara University Medical Faculty, Orthopedics and Traumatology Department, Hand and Upper Extremity Surgery Division, Ankara, Turkey.
Background: Kienböck's disease poses challenges in plate placement during radial shortening osteotomy due to steep metaphyseal inclinations of the distal radius. While coronal plane analyses have been extensively studied, sagittal plane deformities remain underexplored. This study addresses the anatomical variations in the sagittal plane associated with Kienböck's disease.
View Article and Find Full Text PDFNeuroimage
September 2025
Fetal Neonatal Neuroimaging and Developmental Science Center, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA; Division of Newborn Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA; Department of Pediatrics, Harvard Medical School, Boston,
Fetal brain development is a complex and dynamic process, and its disruption can lead to significant neurological disorders. Early detection of brain aberrations during pregnancy is critical for optimizing postnatal medical intervention. We propose a deep generative anomaly detection framework, conditional cyclic variational autoencoding generative adversarial network (CCVAEGAN), that can identify structural brain anomalies using fetal brain magnetic resonance imaging.
View Article and Find Full Text PDFCell
August 2025
Department of Systems Biology, UT MD Anderson Cancer Center, Houston, TX 77030, USA; MD Anderson UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030, USA; Department of Bioinformatics, UT MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:
Understanding epithelial lineages of breast cancer and genotype-phenotype relationships requires direct measurements of the genome and transcriptome of the same single cells at scale. To achieve this, we developed wellDR-seq, a high-genomic-resolution, high-throughput method to simultaneously profile the genome and transcriptome of thousands of single cells. We profiled 33,646 single cells from 12 estrogen-receptor-positive breast cancers and identified ancestral subclones in multiple patients that showed a luminal hormone-responsive lineage, indicating a potential cell of origin.
View Article and Find Full Text PDFSci Adv
September 2025
Department of Applied Physics, The Hong Kong Polytechnic University, Hong Kong 999077, China.
Optical superposition natural compound eyes (OSNCEs) allow circadian insects to thrive in varying light conditions thanks to their unique anatomical structures. This provides a blueprint for optical superposition artificial compound eyes (OSACEs) that can adapt to different illumination intensities. However, OSACEs have received limited research attention until recently, with most studies focusing on apposition compound eyes that operate only in bright light.
View Article and Find Full Text PDFAnat Sci Int
September 2025
Department of Radiology, University of Health Sciences, Istanbul Haseki Training and Research Hospital, Istanbul, Turkey.
The transverse facial artery is a key vascular structure supplying the lateral face and is critically important in surgical procedures such as facelifts, facial trauma repair, and injectable treatments. However, detailed anatomical studies on the transverse facial artery remain scarce. This study aimed to comprehensively evaluate the anatomical variations, depth, branching patterns and clinical significance of the transverse facial artery (TFA) using both cadaveric dissection and computed tomography angiography (CTA).
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