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Article Abstract
Small extracellular vesicles (sEVs) play a crucial role in intercellular communication, but their nanoscale size and heterogeneity make analysis challenging. This study introduces a scalable method for fabricating disk carbon fiber ultramicroelectrodes (UMEs) with precise size control. Size-matched UMEs enable single-sEV detection blocking collisions, achieving a high signal-to-background ratio and low noise. This approach offers unprecedented resolution in determining sEV concentration and size distribution.
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| http://dx.doi.org/10.1039/d5cc00793c | DOI Listing |
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