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Objective: The purpose of this study was to evaluate the impact of upper airway narrowing on patient tolerance in office-based laser surgery.
Study Design: Retrospective chart review.
Methods: All patients who underwent office-based blue laser surgery for benign and premalignant laryngeal lesions between November 2021 and September 2024 were reviewed. The Iowa Satisfaction with Anesthesia Scale questionnaire and the Visual analogue scale score for discomfort were used. Demographic data included age, gender, smoking, Body mass Index, comorbidities, and etiology of dysphonia. Four anatomical sites of the upper airway were evaluated for the presence of narrowing: the nose, nasopharynx, oro-/hypopharynx, and larynx.
Results: A total of 89 patients were included. The most common site of upper airway narrowing was the nose in 74.1% of the cases. This was followed by the nasopharynx and oro-hypopharynx in 23.5% and 20.2% of the cases, respectively. Only 11 patients had laryngeal narrowing with the most common cause being prolapse of the epiglottis. The mean IOWA score of the study group was 1.5 ± 1.1. There was no significant difference in the mean IOWA score between those with or without laryngeal narrowing. The mean VAS score was 2.98 ± 2.47. There was also no significant difference in the mean VAS discomfort score in patients with or without upper airway narrowing, except in those with oro-/hypopharyngeal narrowing (P = 0.011).
Conclusion: Upper airway narrowing had a nonsignificant impact on patient tolerance and discomfort. Nevertheless, patients with narrowing of the upper airway require diligent handling of the endoscope to reduce any potential discomfort.
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http://dx.doi.org/10.1016/j.jvoice.2025.02.015 | DOI Listing |
Sleep Med Rev
August 2025
Department of Pediatrics, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV, USA.
Pediatric obstructive sleep apnea (OSA) is a common yet often underdiagnosed condition, partly due to limited access to polysomnography. Mandibular jaw movement (MJM) analysis offers a promising alternative to conventional home sleep apnea testing in children, capturing the dynamic interactions between respiratory drive and upper airway musculature, enabling accurate identification of, and critical insights into, sleep-disordered breathing events. This technical and practical review provides a structured framework for understanding and interpreting MJM signals during sleep in pediatric patients.
View Article and Find Full Text PDFJ Asthma
September 2025
Department of Pulmonary, Critical Care and Sleep Medicine, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India.
Objective: Small airway dysfunction (SAD) is a common feature of bronchial asthma. However, its association with asthma phenotypes remains poorly understood. This study aimed to assess the prevalence of oscillometry-defined SAD in steroid-naïve adult bronchial asthma and to explore its association with asthma phenotypes based on peripheral blood eosinophil count (BEC).
View Article and Find Full Text PDFChin Med J (Engl)
September 2025
Department of Pulmonary and Critical Care Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.
Obstructive sleep apnea (OSA) is a global public health concern characterized by repeated upper airway collapse during sleep. Research indicates that OSA is a risk factor for the development of various diseases, including cardiovascular disease, metabolic disorders, respiratory diseases, neurodegenerative diseases, and cancer. Exosomes, extracellular vesicles released by most cell types, play a key role in intercellular communication by transporting their contents-such as microRNA, messenger RNA, DNA, proteins, and lipids-to target cells.
View Article and Find Full Text PDFCranio
September 2025
School of Dentistry, Department of Medical Biotechnologies, University of Siena, Siena, Italy.
Objective: The aim of this study was to investigate the impact of rapid maxillary expansion (RME) on sleep bruxism (SB) and respiratory indexes in pediatric patients.
Methods: Twenty-four subjects needing orthodontic treatment and with suspicion of obstructive sleep apnea (OSA) were recruited. Before orthodontics, a clinical and anamnestic evaluation as well as a polygraphic recording was performed.
Allergy
September 2025
2nd Department of Internal Medicine, Jagiellonian University Medical College, Kraków, Poland.
Nonsteroidal anti-inflammatory drugs (NSAID)-exacerbated respiratory disease (N-ERD) is a mainly type 2 inflammatory condition that combines asthma, nasal polyps, and hypersensitivity to NSAIDs. Its pathogenesis involves both upper and lower airways, yet most studies to date have examined these compartments separately. It remains unclear whether the molecular mechanisms in the nose, sinuses, and lungs are distinct or overlapping-an important gap, given that clinical manifestations of N-ERD involve both sites.
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