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Background: The use of geosocial networking apps is linked to increased risky sexual behaviors among men who have sex with men, but their relationship with HIV and other sexually transmitted infections remains inconclusive. Since 2015, the prevalence of app use among men who have sex with men in Shenzhen has surged, highlighting the need for research on their spatiotemporal and behavioral patterns to inform targeted prevention and intervention strategies.
Objective: This study aims to investigate the population size, spatiotemporal and behavioral patterns, and mobility of app-using men who have sex with men in Shenzhen using mobile big data. The goal is to inform enhanced and innovative intervention strategies and guide health resource allocation.
Methods: By leveraging mobile big data application technology, we collected demographic and geographic location data from 3 target apps-Blued (Blued Inc), Jack'd (Online Buddies Inc), and Zank (Zank Group)-over continuous time periods. Spatial autocorrelation (Global Moran I) and hot spot analysis (Getis-Ord Gi) were used to identify the geographic clusters. The Geodetector tool (Chinese Academy of Sciences) was adopted to measure spatially stratified heterogeneity features.
Results: From September 2017 to August 2018, a total of 158,387 males aged 15-69 years in Shenzhen used one of the 3 apps, with the majority (71,318, 45.03%) aged 25-34 years. The app user-to-male ratio was approximately 2.6% among all males aged 15-69 years. The estimated population of app-using men who have sex with men in Shenzhen during this period was 268,817. The geographic distribution of app-using men who have sex with men in Shenzhen was clustered, with hot spots primarily located in central and western Shenzhen, while the distribution of HIV testing and counseling was more concentrated in central-eastern Shenzhen. Approximately 60,202 (38%) app-using men who have sex with men left Shenzhen during the Spring Festival, and 37,756 (62.7%) of them returned after the holiday. The destination distribution showed a relatively centralized flow throughout the country, with the largest mobility within Guangdong province (67.7%), followed by lower mobility to Hunan province (7.9%) and other neighboring provinces (3%-5%), such as Jiangxi, Guangxi, and Hubei Provinces.
Conclusions: Shenzhen has a large population of men who have sex with men. The variation and inconsistent spatiotemporal distribution of app use and HIV testing and counseling emphasize the need to adapt traditional venue-based prevention and intervention to identified hot spots and to launch outreach initiatives that extend beyond traditional healthcare settings. Given the relatively high internal and interprovincial mobility of app-using men who have sex with men, further smartphone-based behavioral monitoring could provide valuable insights for developing enhanced and innovative HIV prevention and intervention strategies. Moreover, our study demonstrates the potential of mobile big data to address critical research gaps often overlooked by traditional methods.
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http://dx.doi.org/10.2196/69569 | DOI Listing |
Womens Health Rep (New Rochelle)
August 2025
Division of allergy & Infectious Disease, Department of Medicine, University of Washington, Seattle, Washington, USA.
Background: Women who use drugs (WWUD) experience increasingly worse outcomes from drug use as compared to men. Additionally, transactional sex, unstable housing, and unmet needs may further complicate their ability to get needed health care. To inform the design of gender-based, mobile health services, we sought perspectives on health care service delivery from WWUD and health care and harm reduction professionals (HHRPs) in Seattle, WA.
View Article and Find Full Text PDFBrain Commun
September 2025
Alzheimer's Disease Cooperative Study (ADCS), Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093, USA.
Several studies implicate circadian rhythm disturbances in Alzheimer's disease. However, very little is known about how circadian rhythms are associated with Alzheimer's pathological biomarkers in older adults at early stages of the disease, and how these relationships map onto cognition. This cross-sectional study used 24-h accelerometry data to investigate the relationships between circadian rhythms, amyloid-β (Aβ), tau, and cognition in 68 older adults with objective early cognitive impairment.
View Article and Find Full Text PDFTemperature (Austin)
April 2025
Faculty of Sport Sciences, University of Poitiers, Laboratory, Mobilité, Vieillissement, Exercice (MOVE)-UR 20296, Poitiers, France.
The optimal Whole-body cryostimulation (WBC) exposure duration to reach the target skin temperature may vary depending on individual factors such as age, sex, and body mass index (BMI). Maintaining skin temperatures below 13.6°C is necessary to trigger significant cold-induced analgesia.
View Article and Find Full Text PDFLipids Health Dis
September 2025
Epidemiology, Medical Faculty, University of Augsburg, Stenglingstr. 2, Augsburg, 86156, Germany.
Background: This study aimed to investigate the gender-specific associations of skeletal muscle mass and fat mass with non-alcoholic fatty liver disease (NAFLD) and NAFLD-related liver fibrosis in two population-based studies.
Methods: Analyses were based on data from the MEGA (n = 238) and the MEIA study (n = 594) conducted between 2018 and 2023 in Augsburg, Germany. Bioelectrical impedance analysis was used to evaluate relative skeletal muscle mass (rSM) and SM index (SMI) as well as relative fat mass (rFM) and FM index (FMI); furthermore, the fat-to-muscle ratio was built.
BMC Public Health
September 2025
Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet, 171 77, Stockholm, Sweden.
Background: As populations age, more knowledge is needed on people who extend their working lives. The aim of this study was to explore if prior sickness absence (> 14 days) and/or disability pension (SADP) in mental and/or somatic diagnoses were associated with time until work exit after ages 65-69 and ≥ 70, respectively, among women and men.
Methods: This prospective population-based cohort study included all 65-69-year-olds (cohort65, n = 201,263) and ≥ 70-year-olds (cohort70, n = 93,751) who were in paid work in Sweden in 2014.