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Article Abstract

A new family of azaborine fluorophores, consisting of ten compounds, has been developed that mimics the chromophore of green fluorescent protein, with conformation locked by a hydroxyboron bridge. These fluorophores exhibit fluorescence Stokes shifts up to 100 nm (0.56 eV) and high brightness (>10 M cm) in the 408-525 nm range. Their potential utility for sensing applications was demonstrated by constructing zinc sensors capable of detecting 100 micromolar Zn concentrations in biological systems with two-photon microscopy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11976841PMC
http://dx.doi.org/10.1021/acs.orglett.5c00284DOI Listing

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