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Article Abstract
Three new naphthoquinone-based meroterpenoids (-), including spironaphthomeroterpenoid (), a novel naphthoquinone-based meroterpenoid with a rare [5, 6] spiro-ring skeleton, and naphthablins D and E (-), along with three known analogues (-) were isolated from sp. HBERC-16614. The structures of these compounds, including their absolute configurations, were established by extensive spectroscopic analysis and electronic circular dichroism (ECD) spectrum. The antibacterial activities of compounds (-) were evaluated against , , and . Among them, compound demonstrated potent antibacterial activity against , with a minimum inhibitory concentration (MIC) value of 3.13 µg/mL.
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