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To improve the settling time for high-speed point-to-point motion, a piecewise-model feedforward controller is introduced which utilizes multiple inverse sub-models with bumpless transfer between them. As the transfer function of this bumpless feedforward controller is non-commutative and non-invertible, a set of special perturbation and reference inputs are designed to extract the signals required for computing the gradient of the cost function. In this way, the optimal parameters within different motion phases are found within an integrated process. It is experimentally demonstrated in a wire-bonding machine that the root-mean-square of tracking error is improved by at least 15.3% in settling phase by the proposed data-based tuning method with bumpless feedforward controller, compared with existing tuning methods with uniform feedforward controller.
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http://dx.doi.org/10.1016/j.isatra.2025.02.028 | DOI Listing |
bioRxiv
August 2025
Behavior and Metabolism Laboratory, Champalimaud Research, Champalimaud Foundation, Lisbon, Portugal.
Nutrient state shapes not only what animals eat, but how they eat it. In , protein deprivation prolongs protein-specific feeding bursts, yet the motor mechanism underlying this change remains unknown. Using EM connectomics, we identified a feed-forward pathway from protein-sensitive gustatory receptor neurons to swallowing motor neurons.
View Article and Find Full Text PDFPLoS One
September 2025
College of Electrical Engineering and Control Science, Nanjing Tech University, Nanjing, Jiangsu, China.
The compact arrangement of chemical storage tanks significantly increases the occurrence probability of domino effect accidents. The accident chain length, a critical parameter for assessing accident severity, enables rapid comprehension of potential accident impacts and serves as a foundation for constructing accident scenarios in domino effect risk assessment. This study centers on domino effect accidents within chemical storage tanks and conducting a detailed analysis of factors influencing the accident chain length.
View Article and Find Full Text PDFSci Rep
September 2025
Department of Instrumentation Engineering, MIT Campus, Anna University, Chennai, 600044, Tamil Nadu, India.
Diabetes is a chronic disorder that disrupts the body's ability to regulate blood glucose (BG) levels, leading to dangerous fluctuations such as hypoglycemia and hyperglycemia. In managing Type 1 Diabetes (T1D), the Dual Hormone Artificial Pancreas (DHAP) has emerged as a promising solution for maintaining optimal BG levels by administering both insulin and glucagon. However, the major challenges in DHAPs are slow dynamics in glucose sensing and delayed insulin absorption.
View Article and Find Full Text PDFCommun Biol
August 2025
Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Sciences, Shandong University, Qingdao, Shandong, China.
Shrimp aquaculture is critically important for global food security, but viral diseases like white spot syndrome virus (WSSV) cause devastating economic losses, highlighting the urgent need for effective disease control strategies. While trained immunity has been observed in invertebrates like shrimp after exposure to pathogens, the underlying molecular mechanisms remain elusive. Here we reveal that lysine acetyltransferase KAT8-mediated histone H3K27ac is critical for antiviral defense in shrimp Marsupenaeus japonicus.
View Article and Find Full Text PDFEntropy (Basel)
August 2025
Department of Imaging Neuroscience, UCL Queen Square Institute of Neurology, London WC1N 3AR, UK.
The organization of consciousness is described through increasingly rich theoretical models. We review evidence that working memory capacity-essential to generating consciousness in the cerebral cortex-is supported by dual limbic memory systems. These dorsal (Papez) and ventral (Yakovlev) limbic networks provide the basis for mnemonic processing and prediction in the dorsal and ventral divisions of the human neocortex.
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