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Objectives: This study aimed to investigate the relationship between the number of children and cognitive function trajectories among older Chinese parents.
Methods: A total of 6723 individuals (55% men) aged 50 years and older were followed for 7 years as part of the China Health and Retirement Longitudinal Study (CHARLS). Cognitive function was assessed through episodic memory and mental status tests. The number of children was dichotomised as 'only child' and 'multiple children'. Linear mixed models were used, with the number of children at baseline as the predictor. Covariates including social-demographic factors, health behaviours and health status were adjusted.
Results: Parents with multiple children had poorer baseline cognitive functions (episodic memory: B = -.17, p < .001; mental status: B = -.25, p < .001) and experienced a faster cognitive decline during the follow-up period (episodic memory: B = -.05, p < .001; mental status: B = -.03, p = .005) compared to those with only one child. Gender-stratified analyses indicated that women were more susceptible to cognitive decline than men as the number of children increased.
Conclusions: This study found a negative correlation between the number of children and cognitive performance among older Chinese parents, with the association being stronger in women. These findings enhance the understanding of the impact of offspring on parental well-being in non-Western societies.
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http://dx.doi.org/10.1111/ajag.70009 | DOI Listing |
Kidney360
September 2025
Department of Pediatrics, Division of Pediatric Nephrology, Baylor College of Medicine, Houston, TX, United States.
Background: Dialysis in neonates with ESKD is often associated with multiple comorbidities and the need for more intensified dialysis regimens. With recent advances in prenatal interventions and infant specific KRT, survival of neonates with ESKD has improved over the last decade. Little is known however about the impact on the health care system of improved survival in this population.
View Article and Find Full Text PDFInt J Comput Assist Radiol Surg
September 2025
Division of Plastic and Reconstructive Surgery, Neonatal and Pediatric Craniofacial Airway Orthodontics, Department of Surgery, Stanford University School of Medicine, 770 Welch Road, Palo Alto, CA, 94394, USA.
Background: Alveolar molding plate treatment (AMPT) plays a critical role in preparing neonates with cleft lip and palate (CLP) for the first reconstruction surgery (cleft lip repair). However, determining the number of adjustments to AMPT in near-normalizing cleft deformity prior to surgery is a challenging task, often affecting the treatment duration. This study explores the use of machine learning in predicting treatment duration based on three-dimensional (3D) assessments of the pre-treatment maxillary cleft deformity as part of individualized treatment planning.
View Article and Find Full Text PDFGraefes Arch Clin Exp Ophthalmol
September 2025
Department of Physics of Condensed Matter, Optics Area. Vision Research Group (CIVIUS), University of Seville, Avenida de la Reina Mercedes s/n (41012), Seville, Spain.
Purpose: To analyze the relationship between various visual function parameters (refractive status, visual acuity and contrast sensitivity) and macular pigment optical density (MPOD) values, as well as dietary intake of lutein and zeaxanthin in a pediatric population.
Methods: Thirty-six healthy White pediatric patients participated in this cross-sectional study conducted at the Optometry Clinic (Faculty of Pharmacy, Seville, Spain). MPOD values were measured using the MPSII (Macular Pigment Screener II).
Naunyn Schmiedebergs Arch Pharmacol
September 2025
Department of Pharmacy, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Maternity and Child Health Hospital, Fujian Medical University, #18 Daoshan Road, Fuzhou, Fujian, 350001, China.
Postpartum hemorrhage (PPH) is a life-threatening obstetric complication. We aimed to identify the drugs that associated with PPH based on the FDA Adverse Event Reporting System (FAERS) data, providing scientific evidence for targeted prevention of drug-related PPH risk factors. Data from 2004Q1 to 2025Q1 were extracted from FAERS, and disproportionality analysis was performed to identify potential drug signals.
View Article and Find Full Text PDFJ Community Health
September 2025
Environmental Health Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Hookah use is a growing global health concern, particularly among young adults, with significant misconceptions about its safety. This study aimed to investigate the prevalence of hookah use and its association with knowledge of harmful substances and future susceptibility among university students in Iran. A cross-sectional study was conducted among 561 undergraduate students from Golestan University of Medical Sciences in Iran between April and June 2024.
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