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With the increasing popularity of minimally invasive techniques in thyroid surgery, the transoral endoscopic thyroidectomy vestibular approach (TOETVA) has garnered significant attention. This study aimed to compare the impact of different distances between the observation and operation ports in TOETVA on clinical treatment outcomes. Ninety patients with papillary thyroid carcinoma were retrospectively analyzed. Based on the distance between the observation and operation ports, they were divided into three groups: Group A (2.3-2.7 cm), Group B (less than 2.3 cm), and Group C (more than 2.7 cm). All three groups underwent TOETVA performed by the same surgical team. Operation time, blood loss, postoperative hospital stay, drainage volume, retrieved and metastatic central lymph nodes, postoperative complications, and tumor recurrence were compared among the groups. There were no demographic differences among the three groups. Compared to Groups B and C, patients in Group A had significantly shorter operation times, lower postoperative drainage volumes, and shorter postoperative hospital stays (p < 0.05). There were no significant differences in bleeding amount, retrieved and metastatic central lymph nodes, or incidence of complications among the groups. No postoperative recurrences were observed in any patient. In TOETVA, the best surgical outcomes were achieved when the distance between the observation and operation ports was approximately 2.5 cm (2.3-2.7 cm). This configuration ensures smooth surgical operations and facilitates postoperative rehabilitation, making it worthy of further clinical promotion.
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http://dx.doi.org/10.1038/s41598-025-91392-3 | DOI Listing |
Nanoscale Horiz
September 2025
Theoretical Chemical Physics Group, Research Institute for Materials Science and Engineering, University of Mons, 20 Place du Parc, Mons B-7000, Belgium.
Two-photon spontaneous emission (TPSE) is a second-order quantum process with promising applications in quantum optics that remains largely unexplored in molecular systems, which are usually very inefficient emitters. In this work, we model the first molecular two-photon emitters and establish the design rules, highlighting their differences from those governing two-photon absorbers. Using both time-dependent density functional theory and Pariser-Parr-Pople calculations, we calculate TPSE in three π-conjugated molecules and identify a dominant pathway.
View Article and Find Full Text PDFClin Transplant Res
September 2025
Division of Nephrology, Department of Internal Medicine, Kyung Hee University College of Medicine, Seoul, Korea.
Background: Calcineurin inhibitor (CNI) toxicity is a significant cause of graft dysfunction in kidney transplant recipients, yet distinguishing it from acute rejection (AR) and acute tubular necrosis (ATN) remains challenging. This study investigated the use of urinary mRNA biomarkers as a noninvasive tool for identifying CNI toxicity.
Methods: We retrospectively enrolled 110 kidney transplant recipients and classified them into four groups based on pathological findings: stable graft function (n=35), CNI toxicity (n=25), AR (n=30), and ATN (n=20).
Thyroid
September 2025
Department of Molecular Diagnostics, Department of Endocrinology, The Core Laboratory in Medical Center of Clinical Research, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
is a major cause of congenital hypothyroidism (CH) in Chinese patients, but clinical outcomes for those with biallelic mutations remain unclear. This study aimed to describe the clinical manifestations of CH due to defect. One hundred eighty-one patients with primary CH were recruited initially and were subjected to genetic screening.
View Article and Find Full Text PDFCyberpsychol Behav Soc Netw
September 2025
School of Nursing and Rehabilitation, Shandong University, Jinan, China.
This study examined the interplay between anxiety, depression, rumination, and problematic internet use (PIU) among 24,470 Chinese adolescents (mean age = 14.37 years; 51.60 percent male), with particular attention to socioeconomic status (SES) variations.
View Article and Find Full Text PDFDalton Trans
September 2025
Departamento de Fisica Aplicada-ICMUV, MALTA Consolider Team, Universitat de Valencia, Av. Dr. Moliner 50, 46100 Burjassot (Valencia), Spain.
The impact of external pressure on the characteristics of SrTeO has been thoroughly examined using density-functional theory calculations up to 100 GPa. It has been predicted that SrTeO undergoes three phase transitions in the pressure range covered by this study. A first transition occurs at 2.
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