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Water pollution from hazardous materials, particularly arsenic, downstream of gold mines poses severe environmental and health risks. This study employs a systematic approach to predict water arsenic (WA) levels downstream of gold mines affected by acid mine drainage. WA data from the affected region were collected and preprocessed to standardize the dataset and mitigate overfitting risks. Advanced ensemble machine learning methods, particularly Light Gradient Boosting Machine (LightGBM), with two models developed: a manually-adjusted version and an optimization-based model using Jellyfish Search Optimizer (JSO). The performance of the LightGBM-JSO model was evaluated against a range of ensemble learning models, metaheuristic algorithms, and artificial intelligence techniques. Models were evaluated using mean absolute error (MAE), mean absolute percentage error (MAPE), coefficient of determination (R), root mean square error (RMSE), weighted mean absolute percentage error (WMAPE), mean relative error (MRE), scattered index (SI), ρ, and the Final Rating (FRa) methodology. The LightGBM-JSO outperformed other models, achieving a training phase MAE of 148.763, MAPE of 62.081, R of 0.996, RMSE of 183.692, WMAPE of 0.08, SI of 0.097, ρ of 0.048, and MRE of - 0.379. In the testing phase, it had an MAE of 19.496, MAPE of 10.686, R of 0.990, RMSE of 37.386, WMAPE of 0.136, SI of 0.241, ρ of 0.121, and MRE of 0.03. Uncertainty analysis confirmed the model's reliability with a prediction interval of ± 0.05 mg/L for arsenic concentration. This study provides evidence to support environmental management decisions, providing valuable insights for regulatory bodies, policymakers, and stakeholders to support sustainable mining practices.
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http://dx.doi.org/10.1016/j.jhazmat.2025.137665 | DOI Listing |
medRxiv
August 2025
Department of Pathology and Laboratory Medicine.
Multi-omics data are instrumental in obtaining a comprehensive picture of complex biological systems. This is particularly useful for women's health conditions, such as endometriosis which has been historically understudied despite having a high prevalence (around 10% of women of reproductive age). Subsequently, endometriosis has limited genetic characterization: current genome-wide association studies explain only 11% of its 47% total estimated heritability.
View Article and Find Full Text PDFSmall
August 2025
Center for Molecular Imaging and Nuclear Medicine, School of Life Sciences & School for Radiological and Interdisciplinary Sciences (RAD-X) & The Second Affiliated Hospital of Soochow University, Soochow University, Suzhou, 215123, China.
Iron oxide nanoparticles (IONPs) have wide biomedical applications and are initially considered with minimal immunogenicity. Recent studies reveal that IONPs can activate the immune system through reactive oxygen species (ROS) or interferon regulatory factor (IRF) pathways. However, the exact mechanism remains unclear.
View Article and Find Full Text PDFSci Data
August 2025
LMU Munich, Department of Statistics, Munich, 80539, Germany.
Reliable company-level greenhouse gas (GHG) emissions data are essential for stakeholders addressing the climate crisis. However, existing datasets are often fragmented, inconsistent, and lack transparent methodologies, making it difficult to obtain reliable emissions data. To address this challenge, we present a gold standard dataset containing emission metrics extracted from 139 sustainability reports collected from company websites.
View Article and Find Full Text PDFNano Lett
September 2025
Joint Research Center for Food Derived Functional Factors and Synthetic Biology of IHM, Anhui Provincial International Science and Technology Cooperation Base for Major Metabolic Diseases and Nutritional Interventions, China Light Industry Key Laboratory of Meat Microbial Control and Utilization, Sc
Plasmon resonance energy transfer (PRET) faces critical challenges in achieving precise molecular-scale distance control and non-perturbative operation within single live-cell environments, e.g., the inability to dynamically tune the donor-acceptor distance () at the single molecular dipole level.
View Article and Find Full Text PDFMed Image Anal
August 2025
School of Computation, Information and Technology, Technical University of Munich, Munich, Germany; School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany. Electronic address:
Cardiac magnetic resonance (CMR) imaging is the gold standard for non-invasive cardiac assessment, offering rich spatio-temporal views of the heart's anatomy and physiology. Patient-level health factors, such as demographics, metabolic, and lifestyle, are known to substantially influence cardiovascular health and disease risk, yet remain uncaptured by CMR alone. To holistically understand cardiac health and to enable the best possible interpretation of an individual's disease risk, CMR and patient-level factors must be jointly exploited within an integrated framework.
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