98%
921
2 minutes
20
Medical image segmentation is pivotal in disease diagnosis and treatment. This paper presents a novel network architecture for medical image segmentation, termed TransDLNet, which is engineered to enhance the efficiency of multi-scale information utilization. TransDLNet integrates convolutional neural networks and Transformers, facilitating cross-level multi-scale information fusion for complex medical images. Key to its innovation is the attention-dilated depthwise convolution (ADDC) module, utilizing depthwise convolution (DWConv) with varied dilation rates to enhance local detail capture. A convolution kernel coupled update mechanism and channel information compensation method ensure robust feature representation. Furthermore, the cross-level grouped attention merge (CGAM) module in both encoder and decoder enhances feature interaction and integration across scales, boosting comprehensive representation. We conducted a comprehensive experimental analysis and quantitative evaluation on four datasets representing diverse modalities. The results indicate that the proposed method has good segmentation performance and generalization ability.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.compbiomed.2025.109723 | DOI Listing |
Comput Biol Med
September 2025
U.O.C. Ematologia e Terapia Cellulare, IRCCS Istituto Tumori "Giovanni Paolo II", Bari, Italy.
Artificial intelligence is revolutionizing health care, particularly in precision medicine and noninvasive diagnostics. Anemia, which is a widespread condition that affects billions of people worldwide, compromises oxygen transport due to low hemoglobin levels, which leads to severe complications if left undetected. Early and frequent monitoring is essential, yet traditional blood tests can be invasive, costly, and impractical for continuous assessment.
View Article and Find Full Text PDFEur J Radiol
September 2025
Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Rationale/objectives: Image-based vascular biomarkers may help expedite evaluation of chronic thromboembolic pulmonary hypertension (CTEPH), which remains difficult to diagnose despite available effective therapies. We sought to determine if vascular heterogeneity and central redistribution on chest CT differed between CTEPH, pulmonary arterial hypertension (PAH), and control groups.
Materials/methods: We retrospectively included 108 patients who underwent right heart catheterization and chest CT (2011-2018).
Mult Scler Relat Disord
September 2025
Department of Neurology, The First Medical Center of PLA General Hospital, Beijing, China. Electronic address:
Background: Differentiating ischemic myelopathies from inflammatory demyelinating diseases is challenging due to overlapping imaging and clinical manifestations. Needle electromyography (EMG) is highly sensitive to spinal anterior horn damage.
Objectives: This study investigates the diagnostic value of spontaneous EMG activity in distinguishing ischemic myelopathies from inflammatory demyelinating diseases.
J Pharmacol Exp Ther
August 2025
Animal Cancer Care and Research Program, University of Minnesota, St Paul, Minnesota; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, Minnesota; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota; Center for Immunology
We evaluated the antitumor effects of remodeling the MC17 mouse sarcoma microenvironment (SME) by targeting urokinase-type plasminogen activator receptor (uPAR)- and epidermal growth factor receptor (EGFR)-expressing cells. Specifically, we used eBAT (a bispecific ligand-targeted toxin directed to EGFR and uPAR), and its mouse counterpart, meBAT, to ablate uPAR- and/or EGFR-expressing cells. We chose the MC17 model because the cells are resistant to eBAT, allowing us to exclusively evaluate the role of uPAR- and EGFR-expressing cells in the SME.
View Article and Find Full Text PDFAm J Case Rep
September 2025
Department of Orthopaedic Surgery, Fukushima Medical University School of Medicine, Fukushima, Japan.
BACKGROUND Periprosthetic tibial fractures following total knee arthroplasty (TKA) are increasingly encountered in very elderly patients, where multiple comorbidities and osteoporosis compromise early mobilization and elevate the risk of complications. Maintaining pre-injury activities of daily living (ADL) while ensuring safe surgical management is challenging. We present a case of a 95-year-old woman with a periprosthetic tibial shaft fracture managed with open reduction, additional plate fixation, and Ilizarov external fixation, enabling immediate postoperative weight-bearing.
View Article and Find Full Text PDF