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Tuberculosis (TB), caused by , remains a global health challenge, despite being preventable and curable. The global goal to end TB by 2030, with India targeting a 90% reduction in TB incidence by 2025, demands comprehensive interventions in prevention, early detection, treatment, and capacity building. This study analyzes the 2023 Global TB Reports, published articles, guidelines, and data to explore India's current TB landscape. Despite progress in diagnostics and TB preventive treatment, significant challenges persist in accessibility, adherence, and treatment completion. Although advancements in household contact screening and TB preventive treatment initiation are notable, gaps in reporting, diagnostic algorithms, and adherence remain. Innovative diagnostic tools and shorter treatment regimens show promise but require more comprehensive implementation. India's strategy for TB elimination focuses on policy expansion, community engagement, and system enhancements. Continuous innovation, rigorous evaluation, and collaborative efforts are crucial to overcoming challenges and meeting TB elimination targets.
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http://dx.doi.org/10.1016/j.ijregi.2024.100556 | DOI Listing |
BMC Psychiatry
September 2025
Department of Cardiovascular, The Second Affiliated Hospital of Nanchang University, No. 1 Minde Road, Jiangxi, Nanchang, 330006, China.
J Neurol
September 2025
Department of General Practice, The First People's Hospital of Lin'an District, Hangzhou, Lin'an People's Hospital Affiliated to Hangzhou Medical College, Hangzhou, 310000, Zhejiang Province, China.
Anti-mGluR1 encephalitis is a rare autoimmune disorder manifesting with cerebellar syndrome with varying levels of severity. However, limited data exist regarding the clinical features and treatment strategies for patients suffering from encephalitis associated with anti-mGluR1 antibodies. Herein, we comprehensively review and discuss clinical features of anti-mGluR1 encephalitis to enhance our understanding of this rare disorder.
View Article and Find Full Text PDFHypertens Res
September 2025
Cardiovascular, Renal, Metabolism Epidemiology, BioPharmaceuticals Medical, AstraZeneca, Cambridge, UK.
This study examined trends in the proportion of adults with self-reported hypertension and in antihypertensive medication use among community-dwelling Australian adults. We analysed data from a longitudinal panel study, covering four waves: 2009 (n = 8023), 2013 (n = 11,475), 2017 (n = 12,843), and 2021 (n = 14,571) for adults aged 18-74 years. Hypertension and antihypertensive medication use were self-reported.
View Article and Find Full Text PDFNat Rev Neurol
September 2025
Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.
Health disparities are preventable differences in health between different populations, and they are endemic throughout medicine owing to social, economic and environmental disadvantages. Neurology is no exception, and health disparities for systematically marginalized groups are present in the prevention, diagnosis, treatment and outcomes of all neurological disorders. The aetiology of these disparities is complex and multifactorial, reflecting the interplay of structural, institutional and individual-level factors.
View Article and Find Full Text PDFNature
September 2025
Department of Translational Genomics, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Small cell lung cancer (SCLC) is a highly aggressive type of lung cancer, characterized by rapid proliferation, early metastatic spread, frequent early relapse and a high mortality rate. Recent evidence has suggested that innervation has an important role in the development and progression of several types of cancer. Cancer-to-neuron synapses have been reported in gliomas, but whether peripheral tumours can form such structures is unknown.
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