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Ambiguity about whether the histidine-rich calcium-binding protein-coding gene (His) or the pore-forming toxin-like gene (PFT) or both are responsible for Fusarium head blight (FHB) resistance conferred by the Fhb1 quantitative trait locus hinders progress toward elucidating Fhb1 resistance mechanisms. Here, with a series of developed lines with or without PFT but all possessing His and five His-carrying PFT mutant lines created via gene editing, we show that PFT does not confer FHB resistance and that the His resistance effect does not require PFT in the tested conditions. We also show that PFT mutations are not associated with morphological and phenological characteristics that often affect FHB severity.
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http://dx.doi.org/10.1038/s41588-024-02056-3 | DOI Listing |
Fungal Biol
October 2025
University of Tuscia, Department of Agriculture and Forest Sciences (DAFNE), Via San Camillo de Lellis SNC, Viterbo, Italy.
Fusarium Head Blight (FHB), caused by various Fusarium species, is a major threat to global cereal production. F. avenaceum is an important FHB pathogen producing enniatin mycotoxins.
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August 2025
Centro de Genômica e Fitomelhoramento, Faculdade de Agronomia Eliseu Maciel, Universidade Federal de Pelotas, Pelotas 96010-900, Brazil.
head blight (FHB) is a major threat to wheat production that is caused by toxigenic species of the complex. This study aimed to investigate the biochemical and molecular defense responses of Brazilian wheat genotypes (BRS 194, BRS Parrudo, and Frontana) with contrasting FHB susceptibilities following inoculation with (deoxynivalenol producer) and (nivalenol producer). Temporal patterns of antioxidant enzymes, defense-related enzymes, and gene expression ( and ) were analyzed from 12 to 96 h after inoculation.
View Article and Find Full Text PDFPlant Biotechnol J
September 2025
State Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences (ICS), Chinese Academy of Agricultural Sciences (CAAS), Beijing, China.
Plants (Basel)
August 2025
Triticeae Research Institute, Sichuan Agricultural University, Chengdu 611130, China.
Global food security relies on wheat, maize, and soybean, yet their cultivation faces escalating threats from Fusarium head blight (FHB) pathogens. We demonstrate that agricultural intensification enables cross-kingdom root infections by and across these crops. Screening of 180 strains revealed tripartite host infectivity, with transcriptomics uncovering host-adapted virulence strategies.
View Article and Find Full Text PDFMicroorganisms
August 2025
College of Plant Protection, Northwest A&F University, Yangling, Xianyang 712100, China.
The biocontrol strain S10 was isolated from tomato leaf mold. The fermentation broth of strain S10 can effectively control Fusarium head blight (FHB), caused by . Enhancing antifungal activity is essential in advancing its commercialization.
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