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In orchard environments, negative obstacles such as ditches and potholes pose significant safety risks to robots working within them. This paper proposes a negative obstacle detection method based on LiDAR tilt mounting. With the LiDAR tilted at 40°, the blind spot is reduced from 3 m to 0.21 m, and the ground point cloud density is increased by an order of magnitude. Based on geometric features of laser point clouds (such as rear wall height and density, and spacing jump between points), a method for detecting negative obstacles is presented. This method establishes a mathematical model by analyzing changes in point cloud height, density, and point spacing, integrating features captured from multiple frames to enhance detection accuracy. Experiments demonstrate that this approach effectively detects negative obstacles in orchard environments, achieving a success rate of 92.7% in obstacle detection. The maximum detection distance reaches approximately 8.0 m, significantly mitigating threats posed to robots by negative obstacles in orchards. This research contributes valuable technological advancements for future orchard automation.
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http://dx.doi.org/10.3390/s24247929 | DOI Listing |
J Med Ethics
September 2025
Department of Philosophy, Peking University, Beijing, China
Digital phenotyping is a novel approach to assessing individual health conditions by collecting and analysing data generated through interactions with digital devices. Although digital phenotyping is regarded as a promising tool for transforming psychiatric clinical practice, its potential to exacerbate epistemic injustice remains a central ethical concern. However, epistemic injustice in psychiatric digital phenotyping should be understood as rooted in specific forms of ignorance, which are not necessarily negative obstacles.
View Article and Find Full Text PDFBiochim Biophys Acta Mol Cell Res
September 2025
Institute of Cellular and Organismic Biology, Academia Sinica, Taiwan. Electronic address:
Paclitaxel resistance is a major obstacle to achieving long-term remission in patients with triple-negative breast cancer (TNBC), and effective strategies to overcome drug resistance would have significant clinical impact. In this study, we established a paclitaxel-resistant cell clone, T50R, from the human TNBC cell line MDA-MD-231. Intriguingly, these drug-resistant T50R cells required paclitaxel for proliferation.
View Article and Find Full Text PDFPLoS One
September 2025
Discipline of Clinical Pharmacy, School of Pharmaceutical Sciences, University Sains Malaysia, Penang, Malaysia.
Background: Ensuring the safety of medications is a significant public health priority, with developed countries implementing robust pharmacovigilance programs. Despite this, healthcare providers continue to underreport adverse drug reactions (ADRs). This study aims to explore the existing pharmacovigilance system and procedure followed for ADR reporting in selected Dubai hospitals.
View Article and Find Full Text PDFPlant Physiol Biochem
September 2025
Joint FAFU-Dalhousie Lab, College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou, 350002, China; Key Laboratory of Ministry of Education for Genetics, Breeding and Comprehensive Utilization of Crops, Fuzhou, 350002, China.
Melon, a globally important horticultural crop, faces increasing continuous cropping obstacles (CCOs) due to cultivation intensification, with autotoxicity being a primary cause. Autotoxin accumulation severely impacts plant growth, reducing yield and quality. Exogenous silicon (Si) plays an important role in improving plant stress adaptation and is an environmentally friendly element with broad application prospects.
View Article and Find Full Text PDFIEEE Trans Neural Netw Learn Syst
September 2025
In essence, reinforcement learning (RL) solves optimal control problem (OCP) by employing a neural network (NN) to fit the optimal policy from state to action. The accuracy of policy approximation is often very low in complex control tasks, leading to unsatisfactory control performance compared with online optimal controllers. A primary reason is that the landscape of value function is always not only rugged in most areas but also flat on the bottom, which damages the convergence to the minimum point.
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