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Under semi-open brewing conditions, traditional often suffers from unstable flavor quality, including occasional delayed bitterness. To address this issue, a yeast strain, SC-6, was screened for its ability to reduce delayed bitterness. The effects of SC-6 on the flavor and microbial composition of exhibiting high levels of delayed bitterness were also investigated. GC-MS analysis indicated that SC-6 significantly lowered the levels of key delayed bitter compounds, including octanoic acid, ethyl caprylate, benzaldehyde, and phenol, by 54.80 %, 12.21 %, 31.38 %, and 43.23 %, respectively. PCoA analysis demonstrated that SC-6 altered the microbial community of traditional . Correlation analysis indicated that reduced bitter compounds correlated with changed abundances of unclassified_f_Micromonosporaceae, Clostridium_sensu_stricto_1, , , unclassified_o__Enterobacterales, and . These results provide effective guidance for controlling off-flavors in traditional and clarify the role of microorganisms in the production of bitter substances.
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http://dx.doi.org/10.1016/j.fochx.2024.102065 | DOI Listing |
Mol Nutr Food Res
August 2025
Leibniz Institute for Food Systems Biology at the Technical University of Munich, Freising, Germany.
Optimizing plant-based protein intake, such as pea protein hydrolysates (PPHs), may aid in obesity management. This study investigated whether PPHs with varying bitterness and degrees of hydrolysis (DH) differently affect satiety in healthy male participants. In a short-term randomized control trial, 19 moderately overweight men (BMI 25-30 kg/m) consumed boluses of 75 g glucose plus 15 g PPH (control without PPH; PPH1: less bitter, DH = 35%; PPH2: more bitter, DH = 23%).
View Article and Find Full Text PDFCureus
May 2025
Department of Emergency Medicine, Government Medical College and Hospital, The Nilgiris, Ooty, IND.
Background Diabetes mellitus, particularly type 2 diabetes mellitus (T2DM), is a chronic metabolic disorder characterized by persistent hyperglycemia. Alpha-glucosidase inhibitors like miglitol delay carbohydrate absorption, thereby reducing postprandial glucose levels. (bitter melon) has demonstrated hypoglycemic effects in various studies, yet its interactions with pharmaceutical antidiabetic agents remain poorly understood.
View Article and Find Full Text PDFJ Sci Food Agric
June 2025
Institute of Crop Science, Physiology of Yield Stability, University of Hohenheim, Stuttgart, Germany.
Background: Quinoa (Chenopodium quinoa) is valued for its nutritional benefits and resilience to abiotic stresses. However, its commercial use is limited by bitter-tasting saponins on the seeds, necessitating resource-intensive removal processes.
Results: This study demonstrates a single nucleotide polymorphism (SNP), G2078C, in the Triterpene Saponin Biosynthesis Activating Regulator Like 1 (TSARL1) gene, which encodes a basic helix-loop-helix (bHLH) transcription factor, as significantly associated with the non-bitter phenotype in quinoa.
Food Funct
August 2025
Biobased Chemistry and Technology, Wageningen University and Research, Bornse Weilanden 9, PO Box 17, 6708 WG, Wageningen, The Netherlands.
Oleosomes, native lipid droplets abundant in the plant kingdom, especially in oilseeds, can be extracted in simple steps and have been suggested as lipid carriers or natural substitutes for oil droplets in emulsion-like products for foods, cosmetics and pharmaceuticals. Oleosomes are good candidates as lipid carriers the oral route due to their limited hydrolysis during gastric digestion and slow hydrolysis in the small intestinal phase. The factors that affect oleosomes' ability to resist digestion, particularly the influence of their membrane molecular composition and density, remain unknown.
View Article and Find Full Text PDFYakugaku Zasshi
May 2025
Department of Clinical Pharmaceutics, Faculty of Pharmaceutical Science, Mukogawa Women's University.
This review highlights the author's research conducted at Mukogawa Women's University from April 2002 to March 2024. The work is categorized into following three areas: (1) Evaluation of the bitterness of oral medications using a taste sensor, (2) Development of drug delivery systems utilizing poly(lactic-co-glycolic acid) (PLGA), and (3) Clinical pharmaceutical evaluation of various injectable formulations. In section (1), the bitterness of oral medications, both alone and in combination with food or beverages, was quantitatively assessed.
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