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Characterization of methicillin-resistant Staphylococcus aureus in Canadian hospitals: 17 years of the CANWARD study (2007-23).
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Department of Medical Microbiology and Infectious Diseases, Max Rady College of Medicine, University of Manitoba, Room 543-745 Bannatyne Avenue, Winnipeg, Manitoba, Canada R3E 0J9.
Objectives: This study reviewed the patient demographic parameters, molecular characteristics and in vitro antimicrobial susceptibility testing results for MRSA isolates infecting inpatients and outpatients presenting for care to tertiary-care Canadian hospitals between 2007 and 2023.
Methods: DNA sequencing was used to generate spa types. Panton-Valentine leukocidin (PVL) genes were detected by PCR.
A Foodborne Outbreak Associated with ST59- t441-SCC IVa Methicillin-resistant Producing Enterotoxins A and B - Puyang City, Henan Province, China, September 2024.
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Puyang Key Laboratory for Infectious Disease Prevention and Control, Puyang Center for Disease Control and Prevention, Puyang City, Henan Province, China.
What Is Already Known About This Topic?: () represents a clinically significant pathogen and serves as a common causative agent of foodborne intoxication. The strain ST59 constitutes the predominant clone associated with both community-associated methicillin-resistant (CA-MRSA) and hospital-associated MRSA (HA-MRSA) infections. However, staphylococcal food poisoning (SFP) outbreaks attributed to ST59 MRSA have been documented in only a limited number of Chinese cities through retrospective investigations.
View Article and Find Full Text PDFEmergence of ST3390: A novel apigmented MRSA clone from the CC5 Lineage.
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Department of Molecular Biosciences, University of South Florida, Tampa, FL, USA.
Background: One of the most successful and widely-distributed hospital-associated lineages of MRSA is clonal complex 5 (CC5). These strains are known for widespread antibiotic resistance, but less severe disease than CA-MRSA counterparts. Recently, CC5 descendant lineages have appeared globally with hypervirulent properties.
View Article and Find Full Text PDFIdentification of a novel ltaS mutation in daptomycin heteroresistant community-acquired methicillin-resistant Staphylococcus aureus ST72 strains in South Korea.
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Division of Infectious Diseases, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea; Vaccine Bio Research Institute, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Daptomycin has been used globally since 2003, with a corresponding increase in daptomycin nonsusceptible (DNS) Staphylococcus aureus. In South Korea, daptomycin became available in 2020, but emerging resistance has posed early therapeutic challenges. We observed suspected heteroresistance to daptomycin (h-DAP) in community-acquired methicillin-resistant S.
View Article and Find Full Text PDFIncarceration is a key driver of racial disparities in community-associated methicillin-resistant Staphylococcus aureus infections in Cook County, IL.
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July 2025
University of Michigan School of Public Health, Department of Epidemiology, Ann Arbor, MI, USA; University of Michigan School of Public Health, Center for Social Epidemiology and Population Health, Ann Arbor, MI, USA.
Purpose: Describe inequities in community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections and identify social factors contributing to these disparities.
Methods: We characterized census tract-level risk factors for CA-MRSA infections in the Cook County Health (CCH) catchment population in Cook County, IL from 2009 to 2022 using hierarchical Poisson regression models. We conducted mediation analyses to estimate a) the total risk attributable to and b) proportion of between-tract disparities in CA-MRSA accounted for by census tract-level inequities in risk factors.