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This study delves into the combined effects of seasonal climate variations and MIPS1 gene mutations on the germination rates of soybean cultivars TW-1 and TW75. Through comprehensive metabolomic and transcriptomic analyses, we identified key KEGG pathways significantly affected by these factors, including starch and sucrose metabolism, lipid metabolism, and amino acid biosynthesis. These pathways were notably disrupted during the spring, leading to an imbalance in metabolic reserves critical for seedling development. Additionally, MIPS1 gene mutations further altered these pathways, exacerbating the metabolic disturbances. Our results underscore the intricate network of environmental and genetic interactions influencing soybean seed vigor and underscore the importance of understanding these pathways to enhance agricultural resilience and seed quality in fluctuating climates.
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http://dx.doi.org/10.1186/s12870-024-05957-x | DOI Listing |
Glob Chang Biol
September 2025
Chair of Silviculture, Faculty of Environment and Natural Resources, Institute of Forest Sciences, University of Freiburg, Freiburg, Germany.
Mixed-species forests are proposed to enhance tree resistance and resilience to drought. However, growing evidence shows that tree species richness does not consistently improve tree growth responses to drought. The underlying mechanisms remain uncertain, especially under unprecedented multiyear droughts.
View Article and Find Full Text PDFFront Nutr
August 2025
Department of Developmental and Behavioral Pediatrics, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Pudong, Shanghai, China.
Background: Emerging evidence suggests vitamin D plays a dual role in immune regulation, yet its interplay with genetic susceptibility in early-life allergy development remains poorly understood. This prospective cohort study investigated whether cord blood 25-hydroxyvitamin D [25(OH)D] levels interact with immunoregulatory gene variants to influence childhood food allergy risk.
Methods: A total of 1,049 mother-infant pairs from the Shanghai Allergy Cohort were stratified by cord blood 25(OH)D concentrations (<15, 15-25, >25 ng/mL).
Eur Heart J Open
September 2025
Department of Cardiology, Copenhagen University Hospital-Herlev and Gentofte, Copenhagen, Gentofte Hospitalsvej 8, 2900 Hellerup, Denmark.
Aims: Atrial fibrillation (AF) may be associated with adverse influenza-related outcomes. We assessed the relative vaccine effectiveness (rVE) of high-dose (HD-IIV) vs. standard-dose (SD-IIV) inactivated influenza vaccination against cardiovascular and all-cause hospitalizations and all-cause mortality according to history of AF.
View Article and Find Full Text PDFEnviron Epidemiol
October 2025
School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan.
Background: Seasonal variation in mortality results from a combination of environmental, biological, and social factors, with ambient temperature recognized as a key contributor. However, comprehensive assessments disentangling temperature effects from other seasonal influences across a broad range of mortality causes remain limited. This study aimed to quantify and compare the mortality burden attributable to ambient temperature and broader seasonal variation across major causes of death in Spain.
View Article and Find Full Text PDFVet World
July 2025
Estación Experimental Agraria Chincha, Dirección de Servicios Estratégicos Agrarios, Instituto Nacional de Innovación Agraria (INIA), Ica 11770 Peru.
Background And Aim: Hematological parameters are critical indicators of health and physiological status in goats. This study aimed to evaluate the effects of location, feeding regimen, age, and body condition score (BCS) on hematological parameters in Creole goats reared under extensive systems on the southern coast of Peru and to establish context-specific reference values.
Materials And Methods: A total of 111 multiparous goats from nine herds were assessed.