Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: St-elevation myocardial infarction (STEMI) is a serious condition that occurs when the blood flow to one or more coronary arteries is blocked, leading to damage or death of the heart muscle (myocardial injury or necrosis). The present study aimed to compare QTc and QTd intervals in patients with STEMI before and 90 minutes after treatment in Booali Sina Hospital, Qazvin, Iran.
Methods: The present study is an analytical cross-sectional study. Between March 2021 and 2022, 107 patients administered to Booali Sina Hospital, Qazvin, Iran, due to STEMI who underwent primary PCI were enrolled in the study. Data including age, sex, height and weight, disease history, QTc interval before and 90 minutes after treatment, QTd before and 90 minutes after treatment and Ejection fraction values were extracted from the patient's files. Then, the relationship between change in QT and QTd after treatment with response to treatment based on ST Resolution was evaluated. SPSS 20.0 statistical program was used for the statistical analysis. All values are given as mean± standard deviation (SD). A p-value of less than 0.05 was considered as significant.
Results: The observed mean difference in investigated variables of patients, including age, height, weight, and BMI, was not statistically significant between the two groups (response to treatment and non-response to treatment ( > 0.05). Findings demonstrated that the mean QTd 1 in the response to the treatment group was higher compared to the non-response to the treatment group, and this difference was not statistically significant ( = 0.337). It is remarkable that the mean QTd 2 in the response to treatment group was statistically significantly lower than the non-response to treatment group ( = 0.002).
Conclusion: We showed that QTd in the studied patients after primary angioplasty reduced significantly compared to the QTd before the treatment, so the QTd can be considered as a noninvasive measure of the response to the treatment in patients with STEMI.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11644199 | PMC |
| http://dx.doi.org/10.47176/mjiri.38.98 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
fNIRS Biomarkers for Stratifying Poststroke Cognitive Impairment: Evidence From Frontal and Temporal Cortex Activation.
Stroke
September 2025
Department of Rehabilitation Medicine, West China Hospital, Sichuan University, Chengdu, China (H.Z., K.H., Q.G.).
Background: Poststroke cognitive impairment (PSCI) affects 30% to 50% of stroke survivors, severely impacting functional outcomes and quality of life. This study uses functional near-infrared spectroscopy (fNIRS) to assess task-evoked brain activation and its potential for stratifying the severity in patients with PSCI.
Method: A cross-sectional study was conducted at Nanchong Central Hospital between June 2023 and April 2024.
PCISOS Risk Profiles Stratify Heterogeneous Outcomes in Minor Posterior Circulation Ischemic Stroke: A Post Hoc Analysis of the CHANCE-2 Trial.
Stroke
September 2025
Department of Neurology, China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University.
Background: Risk stratification in posterior circulation ischemic stroke (PCIS) is challenging. Although the Posterior Circulation Ischemic Stroke Outcome Score (PCISOS) was developed to address this, its utility in minor PCIS and in identifying homogeneous populations for clinical trials or treatment-responsive subgroups remains uncertain.
Methods: CHANCE-2 (Clopidogrel in High-Risk Patients With Acute Non-disabling Cerebrovascular Events-II) was a multicenter, randomized trial that enrolled patients with minor stroke or high-risk transient ischemic attack who carried CYP2C19 loss-of-function alleles.
siRNAs, tRNAs, and rRNAs in Osteoarthritis: Biological Functions and Therapeutic Opportunities.
Biologics
September 2025
Department of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine, Beijing, People's Republic of China.
Osteoarthritis (OA) is a prevalent chronic disease, characterized by progressive joint degeneration and primarily affects older adults. OA leads to reduced functional abilities, a lower quality of life, and an increased mortality rate. Currently, effective treatment options for OA are lacking.
View Article and Find Full Text PDFWhen Less Could be More: Successful Treatment of Granulomatous Lymphocytic Interstitial Lung Disease with Azathioprine.
Eur J Case Rep Intern Med
July 2025
Servicio de Alergia e Inmunología, Hospital Británico de Buenos Aires, Argentina.
Introduction: Interstitial lung disease is a major complication in patients with common variable immunodeficiency. There are some publications that try to shed light on the pathophysiology of this non-infectious complication, most of them highlight the role of follicular T cells and CD21 B cells. Moreover, there are no guidelines based on randomized controlled studies on the treatment of patients with interstitial lung disease and the published case series or small uncontrolled studies describe a wide range of response rates to treatment.
View Article and Find Full Text PDFRestless Eyes at Night: A Novel Variant of Restless Legs Syndrome.
Eur J Case Rep Intern Med
August 2025
Department of General Medicine, Chiba University Hospital, Chiba, Japan.
Introduction: Restless legs syndrome (RLS) is a common sensorimotor disorder that primarily affects the lower extremities. This condition is characterized by unpleasant sensations and an irresistible urge to move the affected body regions, typically during periods of rest or at night. While RLS most commonly involves the legs, atypical variants affecting other body parts, including the arms, abdomen, face, and even the head, have increasingly been reported.
View Article and Find Full Text PDF