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Graph structures are often used to visualize transmission networks generated using genomic epidemiological methods. However, tools to interactively visualize these graphs do not exist. A browser-based tool allowing users to load and interactively visualize transmission graphs was developed in JavaScript. Associated metadata can be loaded and used to annotate and filter the nodes and edges of transmission networks. The tool is available at jodyphelan.github.io/tgv.
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http://dx.doi.org/10.1093/nargab/lqae158 | DOI Listing |
J Appl Toxicol
September 2025
School of Laboratory Medicine and Bioengineering, Hangzhou Medical College, Hangzhou, China.
Polystyrene nanoparticles (PS-NPs) are prevalent environmental contaminants that can accumulate in biological tissues. This study investigates the effects of PS-NPs on TM4 cells, a Sertoli cell line crucial for maintaining the male spermatogenesis microenvironment.TM4 cells were exposed to PS-NPs (0-100 μg/mL) duration of 24 to 72 h.
View Article and Find Full Text PDFJ Vis Exp
August 2025
Department of Cell Biology and Imaging, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University;
Examining circadian synaptic plasticity requires housing mice under different lighting conditions (light/dark cycle, LD 12:12, and constant darkness, DD), providing access to running wheels, and sacrificing them at four defined time points within 24 h-at the beginning and middle of the day/subjective day and at the beginning and middle of the night/subjective night. Brains are then properly fixed for transmission electron microscopy (TEM). The barrel cortex, with its precise somatotopic organization, provides an ideal model for such analysis.
View Article and Find Full Text PDFJ Am Chem Soc
September 2025
Institute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Soochow University, Suzhou 215123, Jiangsu P. R. China.
Advances in molecular analysis and characterization techniques should revolutionize the methods for scientific exploration across physics, chemistry, and biology, fundamentally overturning our understanding of interactions and processes that govern molecular behavior at the microscopic level. Currently, the absence of a molecular analysis method that can both quantify molecules and achieve single-molecule spatial resolution hinders our study of complex molecular systems in sorption and catalysis. Here, we propose a quantitative analysis strategy for small molecules confined in ZSM-5, a zeolite material extensively used in catalysis and gas separation, based on low-dose transmission electron microscopy.
View Article and Find Full Text PDFTransbound Emerg Dis
September 2025
Federal Research Center for Virology and Microbiology - Branch in Nizhny Novgorod, Nizhny Novgorod, Russia.
This study aims to identify the role of various natural, socioeconomic, and demographic factors in the development of the African swine fever (ASF) epizootic among wild boar in the Russian Federation (RF) from 2007 to 2023. In this study, particular emphasis was placed on testing the significance of wild boar population density as a key factor contributing to the spread of ASF within this population. During the study period, 1711 outbreaks in wild boars were reported in the RF, accounting for 41.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
September 2025
Institute of Functional Molecules, Shenyang University of Chemical Technology, Shenyang 110142, China.
A new variety of nitrogen-doped carbon dots (NCDs) was produced using a hydrothermal synthesis method, based on propanedioic acid and barbituric acid as the sources of carbon and nitrogen. The NCDs were analyzed by X-ray photoelectron spectroscopy (XPS), transmission electron microscopy (TEM), Zeta Potential,X-ray Diffraction(XRD),Thermogravimetry-Derivative Thermogravimetry(TG-DTG),Fourier transform infrared spectroscopy (FTIR) and Fluorescence Lifetime. The characterization results indicate that NCDs possess an average diameter of approximately 2.
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