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Cobalamin, generally known as vitamin B, is a crucial component required for humans in several physiological processes. It has been produced from sources that are derived from animals, making it difficult for vegetarians and vegans to consume the recommended amount each day. The importance of vitamin B in red blood cell production, DNA synthesis, and brain processes has been highlighted. Recent studies have looked at different methods of producing vitamin B, such as microbial fermentation. and have demonstrated remarkable potential as fermented sources of vitamin B. Compared to conventional sources, the bioavailability of vitamin B produced by and is more effective in meeting dietary needs. Vitamin B can be produced naturally by . It is equipped with the enzymes and metabolic pathways required to produce this vital vitamin. The fermentation of several dietary substrates by can improve nutrient bioavailability. generates enzymes during fermentation that aid in the breakdown of complex nutrients, facilitating easier absorption and utilization by the body. The motive of the following critical evaluation is to assess the advantages of vitamin B for health and the capacity of and to produce it through fermentation.
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http://dx.doi.org/10.1002/fsn3.4428 | DOI Listing |
Calcif Tissue Int
September 2025
Department of Endocrinology, Post-Graduate Institute of Medical Education and Research (PGIMER), 001, Nehru Extension Block, Chandigarh, India.
Rare diseases, defined by the 2002 Rare Disease Act, affect fewer than 5 in 10,000 individuals. Rare metabolic bone diseases (MBDs), such as osteogenesis imperfecta, hypophosphatasia, osteopetrosis, and other unclassified disorders, can disrupt bone development and remodeling, posing diagnostic and management challenges. This study analyzed data from the rarembd.
View Article and Find Full Text PDFMol Nutr Food Res
September 2025
University of Southampton, Southampton, Hampshire, UK.
Potatoes are a global staple, yet their nutritional potential is underutilized. This study evaluates the biochemical and nutritional composition of Solanum okadae (S. okadae), a wild diploid potato species, compared to the cultivated S.
View Article and Find Full Text PDFClin Nutr ESPEN
September 2025
College of Nursing, University of Kentucky 751 Rose Street Lexington, Kentucky 40536.
Background: Oxidative stress (OS) accelerates the pathogenesis of coronary artery disease (CAD) by contributing to atherosclerotic plaque formation. Current research indicates that antioxidants can mitigate OS by reducing the production of free radicals. Despite many studies that have tested the effects of antioxidants on oxidative stress in patients with CAD, the literature still lacks an updated and comprehensive systematic review.
View Article and Find Full Text PDFInt J Biol Macromol
September 2025
Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiao Tong University, Minhang, Shanghai, 200240, China. Electronic address:
Vitamin A deficiency is one of the most severe micronutrient-related health issues worldwide. Tomatoes, a widely cultivated crop for their adaptability, nutritional value, and lycopene content (a beta-carotene precursor), are ideal candidates for biofortification. In this study, CRISPR-mediated knockout mutants (cr-SlLCYe and cr-SlBCH) were generated to enhance the precursor supply to the β-carotene biosynthetic pathway and reduce its degradation.
View Article and Find Full Text PDFClin Nutr
August 2025
Department of Nephrology, Naval Medical Center of the People's Liberation Amy (PLA), Naval Medical University, Shanghai, China. Electronic address:
Background: Micronutrient deficiencies are common in patients undergoing maintenance hemodialysis (MHD), potentially contributing to adverse clinical outcomes. Hemodiafiltration with endogenous reinfusion (HFR) integrates convection, diffusion, and adsorption, potentially preserving essential nutrients better than traditional online hemodiafiltration (HDF). This study aimed to compare the acute effects of HFR and HDF on serum micronutrient concentrations in MHD patients.
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