Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Objective: This study aimed to describe trends in incidence of gestational diabetes in Manitoba and within subgroups that often experience health inequities.

Methods: We leveraged provincial administrative health data to describe trends in gestational diabetes incidence between 1981 and 2019, stratified by subpopulations based on age, urbanicity, and neighbourhood-level average household income. We calculated yearly incidence across subgroups and annual percent change in incidence to assess trends over time. Geospatial mapping was used to visualize changes by neighbourhood cluster.

Results: Gestational diabetes incidence increased from 1.3% to 8.6% between 1981 and 2019, with an upward inflection occurring around 2010. The annual percent change (APC) between 1981 and 2009, prior to the inflection point, was 1.9% (95% confidence interval [CI] 1.4% to 2.5%), and it was 11.7% (95% CI 8.9% to 14.7%) postinflection---from 2010 to 2019. After 2010, gestational diabetes incidence increased most among urban residents (APC 18.1%, 95% CI 13.9% to 22.5%), among those >35 years of age (APC 12.0%, 95% CI 8.4% to 15.7%), and among individuals in the highest socioeconomic status (SES) group (APC 14.8%, 95% CI 9.4% to 20.4%). Geospatial mapping showed that incidence increased more in neighbourhoods with the highest proportion of recent immigrants to Canada.

Conclusions: Incidence of gestational diabetes increased 6-fold in Manitoba over the past 20 years, particularly among those with high SES and higher age. Further research is required to clarify the role of screening practices in the trends observed in this work.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jcjd.2024.11.005DOI Listing

Publication Analysis

Top Keywords

gestational diabetes
24
1981 2019
12
geospatial mapping
12
diabetes incidence
12
incidence increased
12
trends gestational
8
diabetes manitoba
8
describe trends
8
incidence
8
incidence gestational
8

Similar Publications

Gestational diabetes mellitus (GDM), a type of diabetes mellitus occurring in pregnant women, increases the risk of birth trauma. Solute carrier family 2 member 4 (SLC2A4) polymorphism is notably associated with GDM susceptibility; however, the mechanism is unknown. In the present study, HTR-8/SVneo cells were treated with high glucose concentrations and transfected with SLC2A4 and Forkhead box O (FoxO)1 to investigate their roles in the insulin (INS) resistance of GDM trophoblast cells.

View Article and Find Full Text PDF

Background Subclinical hypothyroidism (SCH) in pregnancy poses serious maternal and fetal risks, including miscarriage, gestational diabetes, and neurodevelopmental impairment. Despite clear international guidelines like those from the American Thyroid Association (ATA), global practice remains inconsistent. In Saudi Arabia, where SCH prevalence among pregnant women is notably high (13%), there is limited national data on how closely physicians follow these guidelines.

View Article and Find Full Text PDF

Objective: To determine the effect of a prepregnancy lifestyle intervention on glucose tolerance in people at higher risk of gestational diabetes mellitus.

Design: Single centre randomised controlled trial (BEFORE THE BEGINNING).

Setting: University hospital in Trondheim, Norway.

View Article and Find Full Text PDF

Objective: To investigate adverse pregnancy and delivery outcomes in women with GDMA1 during pregnancies conceived through fertility treatments.

Methods: This population-based retrospective cohort study examined adverse pregnancy and delivery outcomes in pregnancies affected by GDMA1 following fertility treatments compared to those conceived naturally. Women with GDMA1 who conceived via fertility treatments were classified as cases, while those who conceived naturally were designated as controls.

View Article and Find Full Text PDF

Vitamins, as essential m icronutrients, are vital for numerous cellular functions and play a key role in maintaining hematological parameter s during pregnancy, including erythropoiesis and processes affecting iron status. Iron-Deficient Gestational Anemia (IDGA), the most common clinicopathological condition in obstetrics and highly prevalent in developing countries, significantly contributes to complications such as hypertensive disorders of pregnancy and gestational diabetes. While it is recognized that vitamin deficiencies impact iron metabolism and erythropoiesis, a complete understanding of their specific roles in preventing and managing IDGA is lacking.

View Article and Find Full Text PDF