Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: Controversies still exist regarding the mechanism formation of the blend sign, defined as hypodensity and hyperdensity regions, in Intracerebral Hemorrhage (ICH), and which region associated with bleeding remains unknown. Spot sign is an independent predictor of hematoma expansion (HE) and indicates persistent bleeding focus in the hematoma. Here, we sought to establish the relationship between the spot sign and the blend sign to gain insights into the formation of the blend sign.
Methods: Patients were categorized based on the spot sign location within the blend sign in patients with ICH from 2018 to 2023. subjects with a spot sign in the hypodensity region of the blend sign (hypo-spot sign group); subjects with a spot sign in the hyperdensity region of the blend sign (hyper-spot sign group). Subsequently, patients were stratified into two groups based on the presence or absence of HE. Also, we analyzed the relationship between the spot sign and the blend sign, as well as the association between the blend sign and HE.
Results: A total of 205 patients were included, including 190 patients (92.7%) who had the spot sign in the hyper-spot sign and 15 patients (7.3%) who had the spot sign in the hypo-spot sign. HE was observed in 60 patients (29.3%), 59 (98.3%) of whom had the spot sign detected in the hyper-spot sign, while only one (1.7%) had the spot sign in the hypo-spot sign. Univariate logistic regression analysis revealed that the hyper-spot sign group (6.305, 1.810-49.072; P < 0.05) was an independent predictor of HE.
Conclusion: The hyperdensity area of the blend sign may represent fresh bleeding in ICH rather than the hypodensity area.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.2174/0115734056310498241017052529 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Point-of-care ultrasound of the upper airway in difficult airway management: a systematic review and meta-analysis.
Anaesthesia
September 2025
Department of Anesthesiology and Pain Medicine, Women's College Hospital, and Toronto Western Hospital, University Health Network, Toronto, Canada.
Introduction: The utility of bedside screening tests for the prediction of difficult airways is limited. There is growing interest in the role of point-of-care-ultrasound in airway assessment and management. This systematic review and meta-analysis aimed to determine the diagnostic utility and clinical application of various upper airway point-of-care-ultrasound parameters in the prediction of difficult airways.
View Article and Find Full Text PDFSignature of cooperativity in the stochastic fluctuations of small systems with application to the bacterial flagellar motor.
Sci Rep
September 2025
Laboratoire Charles Coulomb (L2C), Univ. Montpellier, CNRS, Montpellier, France.
The cooperative binding of molecular agents onto a substrate is pervasive in living systems. To study whether a system shows cooperativity, one can rely on a fluctuation analysis of quantities such as the number of substrate-bound units and the residence time in an occupancy state. Since the relative standard deviation from the statistical mean monotonically decreases with the number of binding sites, these techniques are only suitable for small enough systems, such as those implicated in stochastic processes inside cells.
View Article and Find Full Text PDFValue of the spot sign combined with the blend sign for predicting the outcome of patients with intracerebral hemorrhage who have undergone stereotactic minimally invasive surgery.
Front Neurol
August 2025
Emergency Department, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Objective: This study aimed to explore the effect of combining the computed tomographic angiography (CTA) spot sign with the computed tomography (CT) blend sign for predicting the outcome of patients with intracerebral hemorrhage (ICH) who have undergone stereotactic minimally invasive surgery (sMIS).
Methods: Patients with ICH treated with sMIS between January 2018 and April 2023 at the affiliated hospital of Guizhou Medical University were retrospectively included. A modified Rankin scale (mRS) score of ≥3 at 3 months was defined as a poor outcome.
[Visual impairment related to an isolated paracentral cotton wool spot revealing an atypical presentation of Bartonella henselae retinitis].
Rev Med Liege
July 2025
Département d'Anesthésie, Clinique Saint-Luc, Bouge, Belgique.
Cat scratch disease is a bacterial infection due to Bartonella henselae. The microbial agent is most frequently transmitted to humans through a scratch or bite of an infected cat. Ocular involvement occurs in approximately 6% of human infections.
View Article and Find Full Text PDFEvaluation of the remineralization potential of different bioactive glass varnishes on white spot lesions: an in vitro study.
BMC Oral Health
July 2025
Department of Dental Biomaterials, Faculty of Dentistry, Mansoura University, El-Gomhouria street, Mansoura, 35516, Egypt.
Background: White spot lesions represent the first clinical sign of dental caries and can be reversed using various remineralizing agents. This study aimed to synthesize different bioactive glass varnishes and assess their remineralizing effects on white spot lesions compared to fluoride varnish and a synthesized nanosilver fluoride varnish.
Methods: Seventy-two extracted human teeth were used.