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Objective: This study aimed to determine the optimal exercise for improving Upper Crossed Syndrome (UCS) using electromyographic (EMG) activity of upper trapezius (UT), middle trapezius (MT), lower trapezius (LT), and serratus anterior (SA) during ten exercises.
Method: A cross-sectional study involved 30 male students (mean age: 25.3 ± 2.5 years; height: 176.8 ± 7.2 cm; weight: 77.7 ± 2.5 kg; BMI: 23.8 ± 0.72 kg/m) with UCS. Participants were selected based on postural assessments (forward head posture ≥44°, rounded shoulder ≥49°, thoracic kyphosis ≥42°). EMG was used to measure activation levels of UT, MT, LT, and SA, and the UT activation ratio relative to MT, LT, and SA during ten exercises. One-way ANOVA was applied for data analysis.
Results: Side-lying external rotation, standing diagonal flexion with Thera-band, and lying prone "V" demonstrated the least UT activity, with the highest MT and LT activation. The standing diagonal flexion with Thera-band elicited the highest SA activity. UT/MT, UT/LT, and UT/SA ratios were less than one in multiple exercises. Significant differences in muscle activation levels and ratios were observed across all exercises (P ≤ 0.05).
Conclusion: The findings suggest significant clinical implications for UCS rehabilitation. The identified exercises effectively engage MT and LT while minimizing UT activation, addressing muscular imbalances. Favorable UT/MT, UT/LT, and UT/SA ratios further support these exercises in correcting UCS. These exercises may help counteract the underlying muscular imbalance in UCS by promoting a more balanced activity ratio among the shoulder girdle muscles, potentially improving posture and reducing UCS symptoms.
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http://dx.doi.org/10.1016/j.jbmt.2024.09.009 | DOI Listing |
PLoS One
September 2025
Biobank of Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research & The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, Jiangsu, PR China.
Heart failure (HF) and lung cancer (LC) often coexist, yet their shared molecular mechanisms are unclear. We analyzed transcriptome data from the NCBI Gene Expression Omnibus (GEO) database (GSE141910, GSE57338) to identify 346 HF‑related differentially expressed genes (DEGs), then combined weighted gene co-expression network analysis (WGCNA) pinpointed 70 hub candidates. Further screening of these 70 hub candidates in TCGA lung cancer cohorts via LASSO, Random Forest, and multivariate Cox regression suggested CYP4B1 as the only independent prognostic marker.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium.
Objective: This study investigates the mechanisms behind exercise capacity in adults with type 2 diabetes mellitus (T2DM), focusing on central and peripheral components, as described by the Fick equation.
Methods: A cross-sectional study of 141 adults with T2DM was conducted, using cardiopulmonary exercise testing, near-infrared spectroscopy (NIRS) and exercise echocardiography. Participants with sufficient-quality NIRS data were stratified into tertiles based on percentage predicted VO₂peak.
J Appl Physiol (1985)
September 2025
Department of Physical Therapy and Rehabilitation Science, Carver College of Medicine, University of Iowa, Iowa City, Iowa.
Long-term exercise training can attenuate sympathetic vasoconstriction in both resting and contracting skeletal muscle; however, the impact of an acute bout of exercise on vasoconstrictor responsiveness and the influence of aging is unknown. Therefore, we tested the hypothesis that an acute bout of exercise will blunt sympathetic-mediated vasoconstriction in resting and contracting skeletal muscle of young and older adults. Twenty-one adults (10 Young: 23±5 yr and 11 Older: 65±8 yr) performed a rest and a rhythmic handgrip exercise trial before and after either 30 minutes of cycling exercise (60-65% HRmax) or a time control period (seated rest).
View Article and Find Full Text PDFJ Appl Physiol (1985)
September 2025
Ludwig Engel Centre for Respiratory Research, Westmead Hospital, Sydney, NSW, Australia.
Lung volume change modifies pharyngeal airway patency by altering breathing-related passive force transmission between lower and upper airways (via tracheal and other connections). We hypothesise that such force transmission may also impact active upper airway dilator muscle function by altering resting muscle length. The aim of this study was to determine the relationship between end expiratory lung volume (EELV) and ability of sternohyoid muscle (SH) contraction to alter pharyngeal airway patency.
View Article and Find Full Text PDFAm J Physiol Regul Integr Comp Physiol
September 2025
School of Science and Health, Western Sydney University, Sydney, Australia.