Publications by authors named "Lars Louis Andersen"

Purpose: To investigate the associations between different physical activity patterns, including "weekend warrior" (WW) (i.e. most weekly moderate-vigorous physical activity (MVPA) achieved over 1-2 days)) and regular (MVPA spread more evenly) patterns with the risk of incident cancers.

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Purpose: Young workers face higher risks of workplace accidents, mental health issues, and physical strain. This scoping review aims to identify and summarize available research literature on barriers and facilitators to implementing workplace interventions to support young workers' safety, work environment and health.

Methods: We conducted a comprehensive search in bibliographic databases including PubMed, Web of Science and PsycInfo for articles published from 2007-2022.

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Background: While exercise is a key part of knee osteoarthritis (OA) management, the optimal dose for acute pain relief remains unclear. We aimed to determine the optimal resistance exercise volume to induce exercise-induced hypoalgesia (EIH) in older adults with severe knee OA.

Methods: 28 participants (11/17 women/men; mean age = 71.

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Objective: To investigate the dose-response relationship between handgrip strength and incidence of Alzheimer's disease (AD) in middle-aged and older adults.

Design: Longitudinal study.

Patients And Methods: A longitudinal study was conducted in people over 50 years old in 27 European countries and Israel.

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Objective: To examine the one-year impact of a 12-week videoconference-supervised exercise program followed by exercise advice on low back pain (LBP) among eldercare workers.

Methods: 130 participants were randomized to control or intervention arms. Both received standard workplace prevention.

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Genetic factors can influence cardiovascular disease (CVD) risk through multiple behavioral and physiological mechanisms, including lipid metabolism, blood pressure regulation, and inflammatory responses. The present narrative review examines the impact of physical activity on the relationship between genetic susceptibility and CVD risk. Specifically, we synthesize evidence regarding gene-physical activity interplay and whether individuals with a genetic predisposition for CVD benefit more from physical activity than individuals with more health-favorable genotypes.

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Previous meta-analyses show contrasting findings regarding the effects of blood flow restriction training (BFRT) in different knee conditions. Furthermore, no previous dose-response analysis has been conducted to determine the dose of BFRT required for maximal strength and functionality adaptations. To analyze the evidence on the effects of BFRT on strength and functionality in patients with knee osteoarthritis or rheumatoid arthritis through a systematic review with dose-response meta-analysis.

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Objectives: Sustained activity of the upper trapezius muscle during work has been linked to the development of neck pain. Women have higher occurrences of neck pain than men, even in the same occupations. This study aimed to investigate sex-specific associations between upper trapezius muscle activity time-related variables and neck pain using a meta-analysis of pooled data.

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Background/objective: Since muscle strength is modifiable and handgrip strength is a reliable biomarker for strength and mortality, exploring its association with mortality in individuals with severe obesity could help identify protective thresholds. We aimed to examine the dose-response association between handgrip strength and mortality in adults with severe obesity.

Subjects/methods: We retrieved data from the Survey of Health, Ageing and Retirement in Europe (SHARE).

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Objective: To assess the prospective association of chair stand performance with all-cause and cardiovascular mortality in older adults with hypertension.

Methods: From the Survey of Health, Ageing and Retirement in Europe (SHARE) study, we included 18,252 adults aged 50 years or more with hypertension from 28 countries (27 European countries and Israel). Chair stand performance was assessed by the time taken to complete five chair stands.

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The purpose of this study was to provide data-driven recommendations for assessing early-phase rate of torque development (RTD) in isometric knee extension and flexion, focusing on the optimal number of repetitions performed and trial selection criteria to ensure robust intersession reliability. Twenty subjects (10 males, 10 females) completed two test sessions with nine repetitions of unilateral "fast and strong" isometric contractions for the knee extensors and flexors. RTD was calculated from torque onset to 50 ms (RTD50) and 100 ms (RTD100), and peak RTD was assessed in a moving 50 ms interval within the first 100 ms (Peak50).

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Introduction: Europe's aging population calls for ways to prolong working life. Skills development initiatives could potentially improve work ability and extend working lives and may thus be key to address this challenge. However, the role of skills development in relation to work ability and retirement age is still not fully understood.

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Background And Aim: Biomarkers may help predict mortality risk in older adults, yet their combined effects remain unclear. This study aims to identify distinct biomarker profiles in older adults and assess their association with all-cause and cause-specific mortality risk.

Methods And Results: We analyzed data from 12,960 older adults (67.

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Objective: This cross-sectional study assesses the relationship between physical activity and crucial indicators of cognitive function in older adults with osteoarthritis and moderate-severe pain.

Design: Data were derived from the 9th wave of the Survey of Health, Aging and Retirement in Europe, conducted among older people in 27 European countries and Israel. Cognitive measures of verbal fluency, immediate recall, delayed recall, and numeracy were included, as well as self-reports of physical activity level.

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This study assesses the prevalence and trends of depression in the European population aged 50 years and older between 2004 and 2022 in different geographical regions. We retrieved and pooled data from waves 1,2,4,5,6,7,8, and 9 of the Survey of Health, Ageing and Retirement in Europe (SHARE) conducted between 2004 and 2022. The 12-item EURO-D scale was used as a continuous marker of depression risk.

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Background: Little is known about the dose and pattern of moderate-to-vigorous physical activity (MVPA) to prevent depression. We aimed to assess the prospective association of dose and pattern of accelerometer-derived MVPA with the risk of diagnosed depression.

Methods: We included 74,715 adults aged 40-69 years from the UK Biobank cohort who were free of severe disease at baseline and participated in accelerometer measurements (mean age 55.

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Background: Limited knowledge exists on the association between lifestyle factors and pain severity in older adults.

Objective: To assess the associations between unhealthy lifestyle variables and pain severity in the European population of older adults with pain.

Design: Cross-sectional.

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Objective: To investigate the prospective associations between age and the risk of low back disorders (LBD), dorsal disorders (DD), and cervical disorders (CD), and to identify a potential age-threshold for increased risk of back disorders.

Methods: Prospective cohort from the UK Biobank comprising adults with no history of back disorders. We examined different ages and their association with the risk of back disorders derived from diagnoses of hospital registers.

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Objective: To examine the effects on strength, pain intensity, range of motion (ROM), and functionality of a 12-week dual-task resistance exercise program in patients undergoing rehabilitation from elbow fractures.

Design: Randomized controlled trial.

Setting: Rehabilitation hospital.

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The combination of moderate to vigorous physical activity with muscle-strengthening physical activity is increasingly recognized for its significant impact on cardiovascular health. This narrative review synthesizes current evidence to compare the cardiovascular benefits of combined physical activity versus singular forms, especially in primary prevention. The main focus is on hormonal, nervous, genetic, and molecular adaptations, critical mechanisms underlying the body's response to physical activity.

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Purpose: Work-related musculoskeletal disorders are prevalent among healthcare workers. These workers experience high rates of low-back pain; partly due to the high physical demands of patient transfers. Understanding the specific transfer scenarios that contribute to high physical loads is therefore crucial for developing strategies to improve working conditions.

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Objective: This study aimed to determine the optimal exercise for improving Upper Crossed Syndrome (UCS) using electromyographic (EMG) activity of upper trapezius (UT), middle trapezius (MT), lower trapezius (LT), and serratus anterior (SA) during ten exercises.

Method: A cross-sectional study involved 30 male students (mean age: 25.3 ± 2.

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Objective: Knee pain is highly prevalent and disabling among the general and working population. This systematic review explored the effectiveness of workplace-based interventions on knee pain among workers.

Methods: A PICO-guided systematic search was performed in PubMed and Web of Science Core Collection for articles published from 2003 until January 2023.

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Background: There is a dearth of knowledge regarding the relationship between engaging in moderate and vigorous physical activity and long-term sickness absence (LTSA), particularly among various population subgroups such as individuals of different ages or body mass indices. We aimed to evaluate the prospective associations of moderate and vigorous leisure-time physical activity with the risk of LTSA in the general working population.

Methods: A prospective cohort study with a 2-year register follow-up was conducted, where 68,222 representative workers from Denmark completed a questionnaire about work environment, lifestyle, and health.

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Background & Aims: Questions remain whether higher handgrip strength confers additional health advantages beyond adherence to current physical activity guidelines. We aimed to evaluate prospective associations of joint objectively measured handgrip strength and physical activity with incident cardiovascular disease (CVD) and all-cause mortality.

Methods: We analysed the UK Biobank study in a cohort of participants who wore accelerometers for one week, with follow-up based on hospital records until 2022.

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