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To reduce the noise floor in interferometric fiber-optic sensing systems based on 3 × 3 coupler demodulation, this paper proposes spectral subtraction based on multi-window minimum statistical noise estimation to process the two interference signals. This method estimates the noise spectrum of three types of windowed signals, averages these estimation results, and subtracts them from the signal, effectively removing noise from the interfering signal before demodulation, thereby minimizing noise aliasing during demodulation. Subsequently, the ellipse fitting algorithm and the arctangent algorithm are utilized to accomplish signal demodulation. The experimental results indicate that the system's noise floor is reduced by an average of 25 dB within the 0-5 kHz frequency range and achieves a maximum reduction of 30 dB to a level of 0.7 µrad/√Hz at 50 kHz. This scheme does not use additional optics devices, reducing the complexity and cost of the system, and thereby enhancing the feasibility of interferometric fiber optic sensing systems in various environments.
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http://dx.doi.org/10.1364/OE.538312 | DOI Listing |
Sci Adv
September 2025
Department of Physiology, University of Pennsylvania, Philadelphia, PA, USA.
Chromosome motion at spindle microtubule plus ends relies on dynamic molecular bonds between kinetochores and proximal microtubule walls. Under opposing forces, kinetochores move bidirectionally along these walls while remaining near the ends, yet how continuous wall sliding occurs without end detachment remains unclear. Using ultrafast force-clamp spectroscopy, we show that single Ndc80 complexes, the primary microtubule-binding kinetochore component, exhibit processive, bidirectional sliding.
View Article and Find Full Text PDFNanophotonics
August 2025
Wangzhijiang Innovation Center for Laser, Aerospace Laser Technology and System Department, Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai, 201800, China.
The high extinction ratio mode (de)multiplexer is a pivotal component in high capacity mode-division multiplexing data communication and nascent on-chip intermodal acousto-optic modulators. Up to now, high performance on-chip mode (de)multiplexers are still lacking for integrated AOMs on the lithium niobate-on-insulator platform. In this paper, we propose and demonstrate an innovative scheme to achieve high extinction ratio signal routing for acousto-optic modulation, by leveraging a two-mode (de)multiplexer in conjunction with a high- racetrack microring resonator.
View Article and Find Full Text PDFbioRxiv
August 2025
Division of Biological and Biomedical Systems, School of Science and Engineering, University of Missouri-Kansas City, Kansas City, MO 64110 USA.
Voltage-gated sodium (Nav) channels initiate and propagate action potentials in many excitable cells. Upon repetitive activation, the fraction of Nav channels available for excitation gradually decreases on a timescale ranging from seconds to minutes, a phenomenon known as slow inactivation. This process is crucial for regulating cellular excitability and firing patterns.
View Article and Find Full Text PDFSci Rep
August 2025
Department of Solid State Physics, Faculty of Physics and Applied Informatics, University of Łódź, Łódź, Poland.
The growing use of advanced composites in critical applications demands reliable, non-destructive testing. Traditional techniques often detect only large defects, missing subtle local property changes that can precede major failures. Microwave spectroscopy offers a promising alternative, probing both structural and dielectric properties with high sensitivity.
View Article and Find Full Text PDFSensors (Basel)
August 2025
Consiglio Nazionale delle Ricerche, Istituto Nazionale di Ottica (INO), Via Campi Flegrei, 34-Comprensorio A. Olivetti, 80078 Pozzuoli, Italy.
Whispering-gallery-mode (WGM) microresonators are amongst the most promising optical sensors for detecting bio-chemical targets. A number of laser interrogation methods have been proposed and demonstrated over the last decade, based on scattering and absorption losses or resonance splitting and shift, harnessing the high-quality factor and ultra-small volume of WGMs. Actually, regardless of the sensitivity enhancement, their practical sensing operation may be hampered by the complexity of coupling devices as well as the signalprocessing required to extract the WGM response.
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