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Background: Left bundle branch area pacing (LBBAP) requires implantation of the lead deep in the interventricular septum. We developed a novel implantation method that does not require dedicated delivery catheters but only a manually shaped 3-dimensional (3D) stiff stylet.
Objective: The aim of the study was to characterize procedural outcomes of this technique when used as a routine approach for LBBAP.
Methods: A case-control study compared procedural outcomes of consecutive patients who underwent pacemaker implantation at 2 centers: one using only the 3D stylet-based LBBAP technique and the other using the conventional catheter-based LBBAP lead implantation.
Results: A total of 400 patients (age, 75.3 ± 9.8 years; 48.5% female) were analyzed and 230 were matched and included in a 1:1 ratio in each arm of the implantation techniques. No differences were observed in the success rate (95.0% vs 94.8%), fluoroscopy time (9.9 minutes vs 9.6 minutes), paced QRS duration (151 ms vs 148 ms), and sensitivity values (8.2 mV vs 8.5 mV) between the 3D stylet-based and catheter-based techniques, respectively. Small differences were observed in V R-wave peak time (73.2 ms vs 76.5 ms) and capture threshold (0.63 V vs 0.83 V), with a higher percentage of confirmed left bundle branch captures (98.3% vs 77.4%) and a numerically higher occurrence of delayed perforations (2/115 vs 0/115) in the 3D stylet group.
Conclusion: LBBAP lead implantation with the use of a manually shaped stiff 3D stylet is feasible and results in comparable outcomes to those achieved with leads implanted by dedicated preshaped delivery catheters.
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http://dx.doi.org/10.1016/j.hrthm.2024.11.016 | DOI Listing |
J Thorac Cardiovasc Surg
September 2025
Deparment of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea. Electronic address:
Objective: To evaluate the impact of CT planning on surgical myectomy outcomes in patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) and/or mid-cavity obstruction, by comparing these outcomes with those of conventional surgical myectomy.
Methods: This prospective cohort study included patients who underwent surgical septal myectomy for HCM with LVOT and/or mid-cavity obstruction between January 2019 and May 2024 at a single tertiary center. In the CT-planned myectomy group, an expert radiologist simulated the target myectomy site through a series of post-processing methods to plan the surgical approach, provide a surgeon's view that closely resembles the actual perspective in the operating room, and present the target myectomy volume.
CNS Neurosci Ther
September 2025
Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Objectives: Unruptured brain arteriovenous malformations (AVMs) typically do not cause aphasia, even when the traditional language areas are affected by the nidus. We attempted to elucidate its language reorganization mechanism by analyzing the alterations in functional connectivity using functional connectivity (FC) and track-weighted static functional connectivity (TW-sFC) approaches.
Methods: This cross-sectional study prospectively enrolled patients with AVMs involving left-hemisphere language areas and healthy controls.
Can J Cardiol
September 2025
Department of Cardiology, Ningbo No.2 Hospital, Ningbo, Zhejiang, China.
Background: During the electrode screwing process in left bundle branch pacing (LBBP), the significance of the S wave in lead V6 remains elusive. Our study analyzes the change of the S wave in lead V6 under different patterns of capture and explores its mechanisms.
Methods: This study included 243 cases with criterion of selective LBBP (SLBBP), we performed continuous pacing technique and classified the electrophysiological characteristics observed during the screwing process into four patterns: left ventricular septal pacing (LVSP), non-selective LBBP (NSLBBP) in low output and in the lower output, selective LBBP.
Background: Anti-tachycardia pacing (ATP) delivered from implantable cardioverter defibrillators (ICDs) provides critically timed pacing pulses to terminate ventricular tachycardia (VT). Physiological pacing through left bundle branch area (LBBA) pacing has emerged as a clinically relevant alternative to induce synchronous activation of the ventricles. The main objective of this study was to compare the efficacy and safety of ATP delivered to an LBBA lead and a conventional RV lead.
View Article and Find Full Text PDFEur Heart J Case Rep
September 2025
Cardiology Department, Arrhythmia Section, Virgen del Rocío University Hospital, Avda Manuel Siurot s/n, Seville 41013, Spain.
Background: Bundle branch re-entrant ventricular tachycardia (BBRVT) typically occurs in patients with structural heart disease and conduction abnormalities. Certain genetic mutations may be responsible for conduction disorders leading to BBRVT, especially in young individuals without apparent structural heart disease.
Case Summary: A 17-year-old male with no pathological history was admitted to our institution due to wide QRS complex tachycardia with right bundle branch block morphology and left superior axis.