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This study aimed to investigate the benefits of using three-dimensional (3D)-printed hip joint fixators after intra-arterial chemotherapy (IAC) by inguinal femoral artery puncture in children with retinoblastoma. Overall, 79 cases of retinoblastoma who had undergone IAC through the femoral artery were selected and divided into an observation group of 50 cases and an intervention group of 29 cases according to the hemostasis method employed. The patients in the observation group were treated with sandbags for hemostasis, while those in the intervention group were given 3D-printed hip joint fixators to help immobilize the hips and sandbags. We used the Face, Legs, Activity, Cry and Consolability scale (FLACC), the Wong-Baker Facial Expression Pain Scale, and self-made questionnaires to evaluate demographics, clinical characteristics, pain, complications, satisfaction, and other indicators of the two groups. There were no significant differences in general data, such as age, gender, height, weight, manual compression time, diseased eye, tumor stage, platelet count, puncture times, pain distribution, and total score, between the groups. There was a positive correlation between FLACC pain and the total Wong-Baker pain score (r = 0.599, p < 0.001). During the 2 h of sandbag compression, sandbags were dislodged in the observation group as many as ten times, which was significantly higher than that in the intervention group (up to four times; p < 0.001). This was correlated with a very high score of satisfaction (92.34 ± 19.96 out of 100). The 3D-printed hip fixator is easy to operate, has a low incidence of complications, and saves time and effort. It effectively reduces the incidence of sandbags falling off after IAC in children with retinoblastoma and does not increase the patient's pain. It is a method that could improve hemostasis in young children undergoing IAC by inguinal femoral artery.
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http://dx.doi.org/10.1038/s41598-024-78829-x | DOI Listing |
Front Bioeng Biotechnol
August 2025
Department of Orthopedics, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background: Screw fixation is pivotal for prosthetic stability. For 3D-printed customized acetabular revision prostheses designed for complex, large-scale bone defects, precise adherence to preoperative screw trajectory planning is critical. However, there remains a lack of standardized three-dimensional (3D) evaluation protocols to quantify intraoperative screw angular alignment fidelity relative to preoperative digital plans, hindering universal validation criteria.
View Article and Find Full Text PDFArch Orthop Trauma Surg
August 2025
Sydney University, Camperdown, Australia.
Introduction: Access to custom 3D printed pelvic implants (3DPI) is improving for application in both arthroplasty revision and tumour reconstruction. There is limited evidence regarding the safety and outcomes of such implants for large bony defects of the pelvis. The aim of this study is to report the incidence of complications, patient mortality and implant survival following pelvic reconstruction using custom 3Dprinted prostheses in the setting of extensive pelvic bone defects following pelvic tumour resection or failure of total hip arthroplasty (THA).
View Article and Find Full Text PDFIr J Med Sci
August 2025
Department of Radiology, University Hospital Limerick, Limerick, Ireland.
Background: Training radiology residents to perform CT-guided procedures can be challenging due to limited access to scanner time, competition for procedures with other residents and fellows and the risk of exposing patients to unnecessary additional radiation due to the inexperience of the primary operator. Simulation training has shown great benefit in reducing patient risk and increasing training opportunities. The aim of this study was to assess the impact of a high-fidelity 3D-printed model as an interventional radiology training tool for trainees.
View Article and Find Full Text PDFJBJS Essent Surg Tech
August 2025
Department of Orthopaedics, Faculty of Medicine, St. Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
Background: Over the last 30 years, total ankle arthroplasty (TAA) has become a viable surgical option for end-stage ankle arthritis. The aim of TAA is to relieve pain and preserve ankle joint range of motion, which, by definition, shields adjacent joints. Alignment is essential for the longevity and survival of TAA, since malalignment of TAA components can cause abnormal loading patterns with subsequent polyethylene wear and early implant failure.
View Article and Find Full Text PDFDrug Deliv Transl Res
August 2025
Pharmaceutics and Food Technology Department, Faculty of Pharmacy, Universidad Complutense de Madrid, Plaza Ramón y Cajal s/n, Madrid, 28040, Spain.
Periprosthetic joint infections (PJIs) remain a serious complication following hip and knee arthroplasty, affecting 1-5% of patients in developed countries and posing significant challenges to patients, clinicians, and healthcare systems. Conventional prophylactic strategies, such as antibiotic-loaded bone cement, suffer from limited post-implantation drug release and potential compromise of mechanical integrity. To overcome these limitations, we developed a personalized, 3D-printed implant designed to integrate with the acetabular component of joint prostheses.
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