Impact of Longitudinal Mechanical Ventilation Curriculum on Decay of Knowledge.

ATS Sch

Critical Care Medicine Department, National Institutes of Health Clinical Center, National Heart, Lung, and Blood Institute, Bethesda, Maryland.

Published: June 2024


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Background: Prior evidence suggests that critical care trainees and attendings may have trouble recognizing common, potentially life-threatening mechanical ventilation (MV) waveform asynchronies. Although dedicated workshops may improve knowledge in MV, this knowledge may be prone to decay over time. Longitudinal, preceptorial-based curriculums may prevent this decay in knowledge.

Objective: To determine if the addition of a year-long, longitudinal MV preceptorial curriculum to a two-part, small-group, simulation-based education block curriculum reduces decay in MV knowledge compared with the education block curriculum alone.

Methods: This was a multicenter prospective cohort study including 123 first-year fellows from 12 critical care fellowship programs who completed a two-part simulation-based education block (control) after the first and sixth months of fellowship. Fellows from one of these programs also participated in a year-long preceptorial curriculum (intervention). MV waveform examination scores over time during fellowship were compared between control versus intervention groups.

Results: Mean test scores increased for both control and intervention groups after the education block courses at Months 1 and 6 of fellowship. Mean (standard deviation) test scores at Month 12 were higher for the intervention group than the control group (89.3 [14.8] vs. 47.7 [21.4];  < 0.0001). Between 6 months and 3 years of fellowship, there was a significant decay in test scores for the control group (slope estimate [standard error], -13.4 [1.7];  < 0.0001). However, there was no significant decay in test scores for the intervention group (slope estimate, -2.0 [4.7];  = 0.67; difference in slope estimates, 11.4 [5.0];  = 0.02).

Conclusion: The ability of critical care fellows to identify MV waveform asynchronies declines over fellowship training, despite a dedicated two-part, simulation-based MV educational curriculum. The addition of an MV preceptorial course decreased decay of MV knowledge over the course of fellowship training.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11270233PMC
http://dx.doi.org/10.34197/ats-scholar.2023-0051INDOI Listing

Publication Analysis

Top Keywords

education block
16
mechanical ventilation
8
decay knowledge
8
critical care
8
preceptorial curriculum
8
simulation-based education
8
block curriculum
8
months fellowship
8
test scores
8
curriculum
5

Similar Publications

Forkhead-box-protein P3 (FOXP3) is a key transcription factor in T regulatory cells (Tregs). However, its expression and significance in non-immune stromal cells in the tumor microenvironment remain unclear. Here, we demonstrated FOXP3 expression in stromal fibroblasts of mouse and human gastrointestinal tumors.

View Article and Find Full Text PDF

Background/objective: Manual dexterity is critical for maintaining functional independence and quality of life in older adults, yet limited research has explored training interventions to enhance this skill. This study examined the effect of rhythmic gymnastics (RG) exercise programs, with and without apparatus, on the manual dexterity of older women.

Methods: Seventy-six women, aged over 65 (68.

View Article and Find Full Text PDF

Alpha-lipoic acid attenuates cardiac inflammation of CVB3 induced viral myocarditis via neutrophil-derived YM-1.

Biochim Biophys Acta Mol Basis Dis

September 2025

Department of Cardiology, the Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China; State Key Laboratory of Frigid Zone Cardiovascular Disease, Harbin, 150086, Heilongjiang, China; The Key Laboratory of Myocardial Ischemia, Harbin Medical University, Ministry

Background And Aims: Viral myocarditis is an inflammatory pathology of the myocardium that involves innate immune responses, especially those involving neutrophils. However, strategies targeting neutrophils to alleviate inflammation have not achieved complete success. Alpha lipoic acid (ALA), a natural organosulfur compound, has the capacity to modulate immune cell behavior.

View Article and Find Full Text PDF

Phase separation in innate immunity: Teleost IL6Ra's evolutionary leap against viruses.

Int J Biol Macromol

September 2025

National Demonstration Center for Experimental Fisheries Science Education (Shanghai Ocean University), Shanghai, 201306, China; Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources (Shanghai Ocean University), Ministry of Education, Shanghai, 201306, China; International Resea

Phase separation has been discovered as a new form of regulation in innate immunity. Here, we found that IL6Ra in teleost fish has a unique intrinsic disordered region (IDR) in its amino acid sequence, distinguishing it from the IL6Ra of higher vertebrates. This unique feature endows IL6Ra with the ability to undergo liquid-liquid phase separation, enabling the organism to swiftly initiate an immune response at the early stages of viral infection.

View Article and Find Full Text PDF

Dual-epitope targeting of TSLP to simultaneously block TSLPR and IL-7Rα with a Biparatopic nanobody.

Int Immunopharmacol

September 2025

Key Laboratory for Biorheological Science and Technology of Chinese Ministry of Education, National Local Joint Engineering Lab for Vascular Implants, College of Bioengineering, Chongqing University, Chongqing 400044, China; JinFeng Laboratory, Chongqing, 401329, China. Electronic address: wanggx@cq

Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine that plays a crucial role in the pathophysiology of asthma, initiating multiple allergic cascade responses. Tezepelumab is the only monoclonal antibody currently approved for marketing, which acts by blocking TSLP binding to TSLPR. However, it is reported that a TSLP trap which simultaneously block TSLP binding with TSLPR and IL-7Rα has better efficiency in the repression of TSLP signal pathway.

View Article and Find Full Text PDF