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Purpose: This study aimed to identify distinct trends among Chinese residents based on their health-related quality of life (HR-QoL) outcomes and to analyze the demographic characteristics that contribute to these trends.
Materials And Methods: The study conducted latent class analysis using baseline data obtained from a survey of health service utilization behaviors (from July to December 2016) among residents of Hubei Province, China (N = 1517). Latent classes were used to implement the HR-QoL grouping of different trends among the respondents. Multinomial logistic regression analysis was used to identify demographic characteristic factors affecting HR-QoL in the trend groups.
Results: A three-class model emerged as the most suitable grouping classification for HR-QoL among Chinese residents: the low HR-QoL class, exhibiting a downward trend (5.5%); the medium HR-QoL class, exhibiting an upward trend (12.1%); and the stable HR-QoL class, exhibiting high HR-QoL (82.4%). Participants in the medium class were more likely to be without chronic diseases, aged 45-64 years, and employed than those in the low class. Conversely, urban participants had a higher likelihood of belonging to the low class. Participants in the stable class were more likely to be without chronic diseases, aged 15-44 years or 45-64 years, and employed than those in the low class. Conversely, urban participants had a higher likelihood of belonging to the low class.
Conclusion: Three latent trend classes of HR-QoL were observed, which exhibited distinct characteristics. Residents without chronic diseases, residents under 65 years of age, and employed residents had better HR-QoL than individuals in other classes, while urban residents had poorer HR-QoL than individuals in other classes.
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http://dx.doi.org/10.2147/RMHP.S475022 | DOI Listing |
Semin Cell Dev Biol
September 2025
Key Laboratory of Multi-Cell Systems, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai 200031, China. Electronic address:
Cilia are membrane-covered hair-like organelles built on specialized centrioles and conserved throughout eukaryotic evolution. They are either motile or immotile, serving respectively as versatile signaling antennae or elegant beating nanomachines. Accordingly, their dysfunctions cause a wide variety of developmental and degenerative disorders, which in human are syndromes termed ciliopathies.
View Article and Find Full Text PDFJ Hepatol
September 2025
Department of Neonatal Surgery, Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 100045, China. Electronic address:
Background And Aims: Biliary atresia (BA) is a severe neonatal cholangiopathy characterized by progressive inflammation and fibrosis. We aimed to systematically investigate BA pathology using integrated multi-omics.
Methods: Multi-omics integration of BA and control livers revealed sphingolipid dysregulation.
Environ Int
September 2025
State Key Laboratory of Severe Weather (LASW), Chinese Academy of Meteorological Sciences (CAMS), China Meteorological Administration, Beijing 100081, China.
In the context of global warming, the frequency and intensity of extreme weather events are intensifying. Although cold waves have significant impacts on human health, related research remains insufficient. This study integrates high-resolution population dynamics and temperature data to assess cold exposure risks during cold waves in Beijing, addressing a critical research gap in urban public health.
View Article and Find Full Text PDFInt J Stroke
September 2025
Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Background: Endothelial inflammation is involved in cerebral small vessel disease (CSVD) pathogenesis. Vascular cell adhesion molecule 1 (VCAM-1) and intercellular adhesion molecule 1 (ICAM-1) are biomarkers of endothelial inflammation.
Aims: This study investigated association of VCAM-1 and ICAM-1 with presence of CSVD and CSVD burden.
Acad Psychiatry
September 2025
Peking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Haidian District, No. 51 Hua Yuan Bei Road, Beijing, 100191, China. siti
Objective: The study aimed to explore factors influencing Chinese medical students' career choices, especially in choosing child and adolescent psychiatry (CAP) as their specialty.
Method: A 23-item online survey was conducted among third-year medical students at Peking University Health Science Center to explore the factors currently influencing their career choices, as well as their preferences and factors that influence the choice of CAP as a career specialty. Their preferences for CAP-focused curricula were also surveyed.