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In the context of global warming, the frequency and intensity of extreme weather events are intensifying. Although cold waves have significant impacts on human health, related research remains insufficient. This study integrates high-resolution population dynamics and temperature data to assess cold exposure risks during cold waves in Beijing, addressing a critical research gap in urban public health. We have developed an advanced cold exposure risk assessment framework aimed at uncovering the potential health threats posed by winter cold waves to urban residents. Our findings reveal that population movement between urban and suburban areas significantly affects cold exposure risks, with nighttime dynamics exacerbating exposure levels. Specifically, nighttime population dynamics substantially exacerbate cold exposure levels, while daytime population dynamics, due to the urban heat island effect, to some extent reduce cold exposure risks. Additionally, compared to traditional average temperature metrics, dynamically population-weighted temperatures more accurately reflect actual cold exposure risks. The findings of this study provide valuable insights for urban public health management, emphasizing the importance of considering population mobility in public health strategies for responding to extreme weather events.
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http://dx.doi.org/10.1016/j.envint.2025.109773 | DOI Listing |
Environ Int
September 2025
State Key Laboratory of Severe Weather (LASW), Chinese Academy of Meteorological Sciences (CAMS), China Meteorological Administration, Beijing 100081, China.
In the context of global warming, the frequency and intensity of extreme weather events are intensifying. Although cold waves have significant impacts on human health, related research remains insufficient. This study integrates high-resolution population dynamics and temperature data to assess cold exposure risks during cold waves in Beijing, addressing a critical research gap in urban public health.
View Article and Find Full Text PDFJ Lipid Res
September 2025
Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address:
In an interplay with parenchymal cells of metabolically active organs such as heart and adipose tissues, vascular endothelial cells are important for the regulation of nutrient uptake and organ-specific energy metabolism. Based on high expression of the scavenger receptor B1 (SR-B1) in capillary endothelial cells of white and brown adipose tissue (BAT), we proposed a functional role for this receptor in lipid handling and adaptive thermogenesis. To address this hypothesis, we generated mice with an endothelial-specific knockout of SR-B1 and performed metabolic turnover and indirect calorimetry studies in response to environmental cues such as cold exposure and high fat diet feeding.
View Article and Find Full Text PDFTransfusion
September 2025
Research and Development, Australian Red Cross Lifeblood, Sydney, New South Wales, Australia.
Background: Cold-stored platelets (CSP) are now being used to treat acute bleeding. However, as CSP are less suitable for prophylaxis, both room temperature (RT) platelets and CSP will be required, which complicates inventory management. The production of CSP "on-demand" from RT platelets may be a desirable option.
View Article and Find Full Text PDFISME J
September 2025
Division of Biology and Biological Engineering, California Institute of Technology Pasadena, California, United States.
At methane seeps worldwide, syntrophic anaerobic methane-oxidizing archaea and sulfate-reducing bacteria promote carbonate precipitation and rock formation, acting as methane and carbon sinks. Although maintenance of anaerobic oxidation of methane (AOM) within seep carbonates has been documented, its reactivation upon methane exposure remains uncertain. Surface-associated microbes may metabolize sulfide from AOM, maintain carbonate anoxia, contribute to carbonate dissolution, and support higher trophic levels; however, these communities are poorly described.
View Article and Find Full Text PDFBr J Cancer
September 2025
Center for Cancer Research, Medical University of Vienna, Vienna, Austria.
Background: The cold-shock domain protein YB-1 is overexpressed in pleural mesothelioma (PM) and was shown to contribute to increased cell migration and platinum resistance.
Methods: Phosphorylation of YB-1 at position serine 102 was analysed by immunohistochemistry, immunofluorescence and immunoblotting in PM tissue specimens and cell lines. Intracellular localisation experiments involved immunoblotting, transfection of fluorescent protein-tagged YB-1 and confocal imaging.