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The application of thermosensitive fluorescent supramolecular polymers in advanced optical materials, chemical sensors, artificial optical devices, and external stimulus responses remains underdeveloped. In this study, we introduced a novel method for constructing a mechanically interlocked fluorescent supramolecular polymer utilizing host-guest interactions, including C-H···π interactions and π-π stacking. This polymer exhibits outstanding temperature-sensitive fluorescence properties and is environmentally friendly due to its recyclability. Leveraging the polymer's fluorescence response at critical temperature ranges, we developed a high-temperature warning device. This device utilizes the temperature-sensitive fluorescence characteristic of the polymer to indicate dangerous temperature levels, thereby demonstrating its potential in practical safety applications.
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http://dx.doi.org/10.1021/acs.inorgchem.4c03727 | DOI Listing |
Anal Chim Acta
November 2025
Department of Breast Surgery, General Surgery Center, First Hospital of Jilin University, Changchun, PR China. Electronic address:
Background: Breast-conserving surgery (BCS) is the primary surgical approach for patients with breast cancer. The accurate determination of surgical margins during BCS is critical for patient prognosis; however, time constraints and limitations in current pathological techniques often prevent pathologists from performing this assessment intraoperatively. The inability to reliably assess margins during surgery can lead to incomplete tumor removal and the need for additional surgeries.
View Article and Find Full Text PDFInt J Biol Macromol
September 2025
Department of Chemical Sciences, Ariel University, 70400, Israel. Electronic address:
Doubly His-tagged mCherry red fluorescent proteins are observed to form fibers and sheets at neutral pH in the presence of no more than equimolar amounts of Zn or Ni. These architectures, on the order of 10 μm in extent, are detected with scanning transmission electron microscopy imaging. Far ultraviolet circular dichroism spectroscopy attests to the preservation of the native secondary structure of mCherry, while the emission spectrum reveals the maintenance of the chemical environment of the fluorophore site.
View Article and Find Full Text PDFJ Am Chem Soc
September 2025
State Key Laboratory of Advanced Materials for Intelligent Sensing and Key Laboratory of Organic Integrated Circuits, Ministry of Education & Tianjin Key Laboratory of Molecular Optoelectronic Sciences, Institute of Molecular Plus, Department of Chemistry, Tianjin University, Tianjin 300072, China.
Incorporating boron atoms into organic macrocycles imparts unique chemical, electronic, and optical properties. The concept of making use of dative boron-nitrogen (B ← N) bonds for the construction of macrocycles has been proposed, but very few examples have been prepared with functional structures, much less pillar-like and other prismatic macrocycles, and their various functionalities have not been fully exploited. Here, we introduce a "functional molecular wall" synthetic protocol based on the self-assembly characteristics of B ← N dative bonds to construct highly symmetrical macrocycles, forming a quasi-pentagonal-shaped macrocycle (named [5]pyBN-) with a pillar-like structure.
View Article and Find Full Text PDFLangmuir
September 2025
Advanced Polymer Laboratory, Department of Polymer Science and Technology, Government College of Engineering and Leather Technology (Post Graduate), Maulana Abul Kalam Azad University of Technology, Salt Lake City, Kolkata 700106, West Bengal, India.
This research provides a constructive approach for developing high-performance polymer nanohybrids toward enhancing optoelectronic properties, fluorogenic viscosity sensing, and metal-free electrocatalytic oxidation of glycerol to value-added organic(s). Herein, reduced graphene oxide (RGO) and mildly oxidized RGO (MRGO) are strategically combined with fluorescent electroactive polymers (FEPs) to develop a promising sustainable metal-free electrocatalytic system suitable for amplifying opto-electrochemical properties, multiplatform sensing capacity, and electrocatalytic efficiency. The optimized polymeric counterpart (FEP2) promotes dual-state emission in the supramolecular network of RGO-/MRGO-incorporated fluorescent electroactive hybrid polymers (RFEHPs/MFEHPs) through physicochemically confined atypical electron-rich -C(═O)NH-/-C(═O)O-/-SOH fluorophores of (hydroxyethyl)methacrylate and 2-acrylamido-2-methylpropane-1-sulfonic acid monomers.
View Article and Find Full Text PDFBiol Open
September 2025
Institute of Molecular Biosciences, Mahidol University, 25/25 Phuttamonthon 4 Road, Salaya, Phuttamonthon, Nakhon Pathom 73170, Thailand.
Yeast mitochondrial malate dehydrogenase, Mdh1p, is known to form supramolecular complexes with other TCA cycle and mitochondrial dehydrogenase enzymes, including the aldehyde dehydrogenase, Ald4p. These complexes have been proposed to facilitate NADH channeling. Here, we demonstrate that in cells grown to saturation and stationary phases, the endogenous Mdh1p, expressed without its mitochondrial targeting signal (MTS), stays outside mitochondria, in both a diffuse cytoplasmic distribution as well as localized to distinct puncta.
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