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: This study aimed to evaluate the diagnostic value of pre-existing computed tomography (CT) examinations for the detection of dental pathologies compared with clinical dental examination in patients with end-stage heart failure. : For this purpose, 59 patients with end-stage heart failure and pre-existing non-dental CT images of the craniofacial region were included. Virtual orthopantomograms (vOPG) were reconstructed. Dental pathologies were analyzed in vOPG and source-CT images. Imaging and clinical findings less than 6 months apart were compared ( = 24). : The subjective image quality of vOPG was more often rated as insufficient than CT (66%; 20%; < 0.01). Depending on examination (CT, vOPG or clinic), between 33% and 92% of the patients could require dental intervention such as treatment of caries and periodontitis or tooth extraction. vOPG led to a higher (80%) prevalence of teeth requiring treatment than CT (39%; < 0.01). The prevalence of teeth requiring treatment was similar in CT (29%) and clinic (29%; = 1.00) but higher in vOPG (63%; < 0.01). CT (stage 3 or 4: 42%) and vOPG (38%) underestimated the stage of periodontitis (clinic: 75%; < 0.01). : In conclusion, available CT images including the craniofacial region from patients with end-stage heart failure may contain valuable information regarding oral health status. The assessability of vOPGs might be insufficient and must be interpreted with caution.
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http://dx.doi.org/10.3390/jcm13185406 | DOI Listing |
J Orthop Res
September 2025
Department of Kinesiology, College of Health Sciences, University of Rhode Island, Kingston, Rhode Island, USA.
Arthroplasty surgery is a common and successful end-stage intervention for advanced osteoarthritis. Yet, postoperative outcomes vary significantly among patients, leading to a plethora of measures and associated measurement approaches to monitor patient outcomes. Traditional approaches rely heavily on patient-reported outcome measures (PROMs), which are widely used, but often lack sensitivity to detect function changes (e.
View Article and Find Full Text PDFRen Fail
December 2025
Department of Critical Care Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, China.
This study aimed to develop a predictive model and construct a graded nomogram to estimate the risk of severe acute kidney injury (AKI) in patients without preexisting kidney dysfunction undergoing liver transplantation (LT). Patients undergoing LT between January 2022 and June 2023 were prospectively screened. Severe AKI was defined as Kidney Disease: Improving Global Outcomes stage 3.
View Article and Find Full Text PDFIntern Med
September 2025
Division of Hematology/Oncology, Department of Medicine, Kameda Medical Center, Japan.
We herein report two cases of immunotactoid glomerulopathy (ITG) associated with multiple myeloma treated with daratumumab-based regimens. The first patient was an 81-year-old woman with severe renal insufficiency and IgAκ multiple myeloma (MM) that progressed to end-stage renal disease despite administering daratumumab-based therapy. The second patient, a 69-year-old man with smoldering MM, showed a favorable response to daratumumab-based treatment, with a resolution of nephrotic proteinuria.
View Article and Find Full Text PDFBiomed Phys Eng Express
September 2025
Southwest Jiaotong University School of Mechanical Engineering, No. 111, North Section 1, Second Ring Road, Jinniu District, Chengdu, Chengdu, Sichuan, 610031, CHINA.
Total hip arthroplasty (THA) is the standard surgical treatment for end-stage hip osteoarthritis, with its success dependent on precise preoperative planning, which, in turn, relies on accurate three-dimensional segmentation and reconstruction of the periarticular bone of the hip joint. However, patients with hip osteoarthritis often exhibit pathological characteristics, such as joint space narrowing, femoroacetabular impingement, osteophyte formation, and joint deformity. These changes present significant challenges for traditional manual or semi-automatic segmentation methods.
View Article and Find Full Text PDFClin Nucl Med
September 2025
Department of Radiology and Nuclear Medicine, Comprehensive Cancer Care and Research Center (SQCCCRC), University Medical City, Muscat, Oman.
PSMA-targeted radioligand therapies with 177Lu-PSMA-617 have shown promising response rates with favorable toxicity in patients with metastasized castration-resistant prostate cancer. We report a case of a 72-year-old man with metastatic castration-resistant prostate cancer having comorbidities of DM, HTN, and end-stage renal disease (ESRD) on regular hemodialysis. The patient received 2 doses of 7.
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