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Group-living animals sleep together, yet most research treats sleep as an individual process. Here, we argue that social interactions during the sleep period contribute in important, but largely overlooked, ways to animal groups' social dynamics, while patterns of social interaction and the structure of social connections within animal groups play important, but poorly understood, roles in shaping sleep behavior. Leveraging field-appropriate methods, such as direct and video-based observation, and increasingly common on-animal motion sensors (e.g., accelerometers), behavioral indicators can be tracked to measure sleep in multiple individuals in a group of animals simultaneously. Sleep proximity networks and sleep timing networks can then be used to investigate the collective dynamics of sleep in wild group-living animals.
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http://dx.doi.org/10.1016/j.tree.2024.07.011 | DOI Listing |
Mol Divers
September 2025
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.
Tilorone, a 9-fluorenone scaffold-based molecule, is a known broad-spectrum antiviral with an IC of 180 nM against SARS-CoV-2, but its mechanism is not known. In the present study, we found it to have weak activity against PLpro (IC = 30.7 ± 7.
View Article and Find Full Text PDFSemin Nephrol
September 2025
University of Alabama at Birmingham, Department of Medicine, Division of Nephrology, Section of Cardio-Renal Physiology and Medicine, Birmingham, AL. Electronic address:
Chronic kidney disease of unknown etiology has been reported in Mesoamerican regions and other parts of the world, with increasing evidence pointing to heat stress as a central contributing factor. The incidence of acute kidney injury appears to correlate strongly with heat exposure, as demonstrated in both human and animal studies. The underlying mechanisms of heat-induced kidney injury are likely multifactorial, involving hemodynamic changes, immune responses, and possibly coagulopathies.
View Article and Find Full Text PDFJ Allergy Clin Immunol
September 2025
National Heart and Lung Institute, Imperial College London, London, United Kingdom; Frankland and Kay Allergy Centre, UK NIHR Imperial Biomedical Research Centre, United Kingdom.
Recent advancements in genomics and "omic" technologies have ushered in a transformative era referred to as personalized or precision medicine. This innovative approach considers the unique genetic profiles of individuals, along with a range of variability factors, to devise tailored disease treatments and prevention strategies that cater to the distinct needs of each patient. Although the terms personalized medicine and precision medicine are frequently utilized interchangeably, it is essential to delineate the subtle distinctions between them.
View Article and Find Full Text PDFJ Neurosci Methods
September 2025
Bioengineering College of Chongqing University, Chongqing University Central Hospital (Chongqing Emergency Medical Center), Chongqing, China; Chongqing Key Laboratory of Emergency Medicine, Chongqing, China. Electronic address:
Background: Current neurovascular unit isolation requires processing brain microvascular endothelial cells (BMECs) and neurons from separate animals, preventing concurrent analysis of neurovascular crosstalk within identical genetic/physiological contexts.
New Methods: We developed an enzymatic digestion/bovine serum albumin density gradient technique that enables the simultaneous isolation of neural tissue and microvascular segments from individual mice. The neural tissue was filtered and centrifuged for primary cortical neuron culture on poly-L-lysine-coated plates.
Acta Trop
September 2025
Department of Biology, College of Natural Sciences, Kyungpook National University, Daegu, 41566, Republic of Korea; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea; G-LAMP Project Group, Kyungpook National University,
Culicoides spp. (Diptera: Ceratopogonidae) are vectors of livestock diseases, including bluetongue, Akabane, and African horse sickness. Accurate species identification is a crucial first step in effective vector management.
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