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http://dx.doi.org/10.1016/j.mtbio.2024.101190 | DOI Listing |
Mater Today Bio
October 2024
Hepatobiliary Surgery Department, The First Affiliated Hospital of Hebei North University, Zhangjiakou, Hebei, 075000, China.
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April 2022
Department of Orthopedics and Trauma, Peking University People's Hospital, Peking University, Beijing, People's Republic of China.
Carbon nanotubes (CNTs) have attracted increasing attention in the field of peripheral nerve tissue engineering due to their unique structural and physical characteristics. In this study, a novel type of aligned conductive scaffolds composed of polycaprolactone (PCL) and CNTs were fabricated via electrospinning. Utilizing mussel-inspired polydopamine (PDA) surface modification, brain-derived neurotrophic factor (BDNF) was loaded onto PCL/CNT fibrous scaffolds to obtain PCL/CNT-PDA-BDNF fibrous scaffolds capable of the sustained release of BDNF over 28 d.
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